EOD Primary Tumor

Notes

**Note 1:** **Bilateral involvement** * If both eyes are involved, code the information for the most extensively involved eye in this field. **Note 2:** **CLINICAL AND PATHOLOGICAL codes** * This schema has extension codes that are defined as “CLINICAL assessment only” or “PATHOLOGICAL assessment only” * **CLINICAL** assessment only codes (100, 125, 150, 200, 225, 325, 375, 425, 475, 525, 600, 650, 700) are used when there is a clinical work up only, including physical exam, imaging and biopsy (see **Note 3** for exception) * **PATHOLOGICAL** assessment only codes (175, 250, 275, 350, 400, 450, 500, 750) are used when there is a surgical resection of the primary site (enucleation)(see **Note 3** for exception) * Remaining codes (no designation of CLINICAL or PATHOLOGICAL only assessment) can be used based on clinical and/or pathological information **Note 3:** **Enucleation** * Pathological staging information from an enucleation always takes precedence over clinical staging * *Exception*: cases with neoadjuvant treatment where clinical disease is as extensive as or more extensive than disease at surgery
Code Description SS2018 T
100 **CLINICAL assessment** Intraretinal tumor(s) with subretinal fluid - Equal to but not greater than 3 millimeter (mm) - AND Location not closer than 1.5 mm to optic disk or fovea L
125 **CLINICAL assessment** Intraretinal tumor(s) with subretinal fluid - Greater than 3 millimeter (mm) - AND Location closer than 1.5 mm from disc or fovea L
150 **CLINICAL assessment** Intraretinal tumor(s) with subretinal fluid ≤5 mm from the base of any tumor Tumor confined to retina, NOS Localized, NOS L
175 **PATHOLOGICAL assessment only** Intraocular tumor(s) WITHOUT any - Local invasion - Focal choroidal invasion - Pre- or intralaminar involvement of the optic nerve head Tumor confined to retina, NOS Localized, NOS L
200 **CLINICAL assessment only** Intraocular tumor(s) WITH - Subretinal fluid greater than 5 mm [0.5 cm] from base of tumor - WITH or WITHOUT retinal detachment L
225 **CLINICAL assessment only** Intraocular tumor(s) WITH - Vitreous seeding and/or subretinal seeding - WITH or WITHOUT retinal detachment L
250 **PATHOLOGICAL assessment only** Intraocular tumor(s) WITH local invasion - Concomitant focal choroidal invasion - AND pre- or intralaminar involvement of optic nerve head L
275 **PATHOLOGICAL assessment only** Intraocular tumor(s) WITH local invasion Stromal invasion iris - AND/OR trabecular meshwork - AND/OR Schlemm's canal L
300 Intraocular tumor(s) WITH local invasion, NOS Intraocular tumor(s) with retinal detachment, vitreous seeding, or subretinal seeding, NOS L
325 **CLINICAL assessment only** Advanced intraocular tumor(s) WITH - Phthisis or pre-phthisis bulbi L
350 **PATHOLOGICAL assessment only** Intraocular tumor(s) WITH significant local invasion - Massive choroidal invasion (greater than 3 mm [0.3 cm] in largest diameter) - OR multiple foci or focal choroidal involvement (greater than 3 mm) - OR full-thickness choroidal involvement L
375 **CLINICAL assessment only** Advanced intraocular tumor(s) WITH invasion of - Anterior chamber - Choroid - Ciliary body - Iris - Lens - Pars plana - Zonules L
400 **PATHOLOGICAL assessment only** Intraocular tumor(s) WITH significant local invasion - Retrolaminar invasion of optic nerve head - NOT involving transected end of optic nerve L
425 **CLINICAL assessment only** Advanced intraocular tumor(s) WITH - Raised intraocular pressure with neovascularization - AND/OR buphthalmos L
450 **PATHOLOGICAL assessment only** Intraocular tumor(s) WITH significant local invasion - Any partial-thickness involvement of sclera within inner two thirds L
475 **CLINICAL assessment only** Advanced intraocular tumor(s) WITH - Hyphema AND/OR massive vitreous hemorrhage L
500 **PATHOLOGICAL assessment only** Advanced intraocular tumor(s) WITH - Full-thickness invasion into outer third of sclera - AND/OR invasion into or around emissary channels L
525 **CLINICAL assessment only** Advanced intraocular tumor(s) WITH - Aseptic orbital cellulitis L
550 Advanced intraocular tumor(s) WITH significant local invasion L
600 **CLINICAL assessment only** Extraocular tumor(s) involving orbit - Radiologic evidence of retrobulbar optic nerve involvement - OR thickening of optic nerve and/or orbital tissues RE
650 **CLINICAL assessment only** Extraocular tumor(s) involving orbit, including optic nerve - WITH proptosis AND/OR an orbital mass RE
700 **CLINICAL assessment only** Extraocular tumor(s) involving orbit, including optic nerve, NOS RE
750 **PATHOLOGICAL assessment only** Evidence of extraocular tumor - Tumor at transected end of optic nerve - Tumor in the meningeal spaces around optic nerve Full-thickness invasion of sclera WITH invasion of - Adjacent adipose tissue - Bone - Conjunctiva - Episclera - Extraocular muscle - Eyelids RE
800 No evidence of primary tumor U
999 Unknown; extension not stated Primary tumor cannot be assessed Not documented in medical record Death Certificate Only U
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998 (2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001. (3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05**. American Joint Committee on Cancer (Chicago, IL) (4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017 (5) Mallipatna, A.C., Finger, P.T., et al. **Retinoblastoma**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017