EOD Primary Tumor
Notes
**Note 1:** **Common histology** * Over 90% of penile cancers are squamous cell carcinomas arising in the skin. * Other cancers arising in the skin include adenocarcinomas (5%) arising in sweat glands, melanomas (2%, included in the Melanoma schema), and basal cell carcinoma (2%). About 1% of penile cancers are sarcomas, arising in subcutaneous connective tissues. **Note 2:** **Verrucous carcinoma** * If verrucous carcinoma (8051/3) is described as noninvasive or as having a broad pushing border or penetration, assign code 050. * If verrucous carcinoma is not so characterized, assign code 070, Verrucous carcinoma, NOS. * If there is destructive invasion of verrucous carcinoma into structures in code 100 or greater, assign the appropriate higher code. **Note 3:** **Limited to the penis** * Tumors limited to the penis (see codes 100, 200, 300) include * Dartos fascia (foreskin) * Dermis (foreskin) * Lamina propria (glans and foreskin) * Subepithelial connective tissue (shaft)| Code | Description | SS2018 T |
|---|---|---|
| 000 | In situ, intraepidermal, intraepithelial, noninvasive Bowen disease Carcinoma in situ (Penile intraepithelial neoplasia III [PeIN III]) Erythroplasia of Queyrat | IS |
| 050 | Noninvasive localized squamous cell carcinoma Noninvasive verrucous carcinoma | IS |
| 070 | Verrucous carcinoma, NOS (ICD-O-3 code 8051/3 only) | L |
| 100 | Limited to penis - WITHOUT perineural and/or lymphovascular invasion - WITH low grade (i.e., grade 1-2) or UNKNOWN grade | L |
| 150 | Code 100 WITH high grade (i.e., grade 3 or sarcomatoid) | L |
| 200 | Limited to penis - WITH perineural and/or lymphovascular invasion - WITH or WITHOUT high grade (i.e., grade 3 or sarcomatoid) | L |
| 300 | Limited to penis - UNKNOWN perineural and/or lymphovascular invasion Confined to penis, NOS Localized, NOS | L |
| 400 | Corpus spongiosum (including tunica albuginea) - WITHOUT urethral invasion or UNKNOWN if urethral invasion | RE |
| 450 | Code 400 WITH urethral invasion | RE |
| 500 | Corpus cavernosum (including tunica albuginea) - WITHOUT urethral invasion OR UNKNOWN if urethral invasion | RE |
| 550 | Code 500 WITH urethral invasion | RE |
| 600 | Muscle, NOS - Bulbospongiosus - Ischiocavernosus - Superficial transverse perineal Prostate Pubic bone Scrotum Skin (abdominal, perineum) | RE |
| 700 | Further contiguous extension - Testis | D |
| 800 | No evidence of primary tumor | U |
| 999 | Unknown extension Primary tumor cannot be assessed Not documented in medical record Death Certificate Only | U |