EOD Primary Tumor

Notes

**Note 1:** **Multifocal tumors** * In case of multifocal papillary noninvasive tumors (code 000) and nonpapillary in situ tumors (code 050), code 050. **Note 2:** **Involvement of both renal pelvis and ureter** * Tumor involving both renal pelvis and ureter (unifocal or multifocal) is classified by the depth of greatest invasion in either organ. **Note 3:** **Ureter tumor with bladder invasion** * Direct invasion of the bladder by a ureteral tumor is classified by the depth of greatest invasion of the bladder or ureter.
Code Description SS2018 T
000 Papillary (8130/2, 8131/2, other histologies, see code 050) - Non-infiltrating or non-invasive papillary transitional cell carcinoma - Non-infiltrating or non-invasive papillary urothelial carcinoma - Papillary transitional cell carcinoma, with inferred description of non-invasion - Papillary urothelial carcinoma, with inferred description of non-invasion IS
050 Nonpapillary - Carcinoma in situ, NOS - Sessile (flat) (solid) carcinoma in situ - Transitional cell carcinoma in situ - Urothelial carcinoma (in situ, non-infiltrating, non-invasive) Multifocal papillary and nonpapillary non-invasive tumors (see Note 1) IS
100 Subepithelial connective tissue (lamina propria, submucosa) of renal pelvis only OR Subepithelial connective tissue (lamina propria, submucosa) of ureter only Confined to renal pelvis, NOS Confined to ureter, NOS Localized, NOS L
200 Renal pelvis and ureter (unifocal or multifocal) - Subepithelial connective tissue + Renal pelvis from ureter + Ureter from renal pelvis + Distal ureter from proximal ureter Extension to bladder from ureter - Subepithelial connective tissue of distal ureter and/or bladder RE
300 Muscularis of renal pelvis only OR Muscularis of ureter only L
400 Code 200 + 300 Renal pelvis and ureter (unifocal or multifocal) - Muscularis + Distal ureter from proximal ureter + Renal pelvis from ureter + Ureter from renal pelvis Extension to bladder from ureter - Muscularis of distal ureter and/or bladder RE
500 Extension to/Invasion of beyond muscularis into - Peripelvic fat (renal pelvis) - Periureteric fat (ureter) - Retroperitoneal soft/connective tissue For renal pelvis only - Ipsilateral kidney parenchyma and kidney, NOS RE
600 Extension to/Invasion of * Duodenum (from right renal pelvis or right ureter) * Ipsilateral adrenal (suprarenal) gland * Major blood vessel(s) - Aorta - Renal artery/vein - Vena cava (inferior) * Psoas muscle (ureter) * Tumor thrombus in a renal vein, NOS RE
700 Extension to/Invasion of * Ascending colon (from right renal pelvis or right ureter) * Bladder (wall or mucosa) from renal pelvis * Colon, NOS * Descending colon (from right renal pelvis or right ureter) * Ipsilateral kidney parenchyma from ureter * Liver (from right renal pelvis or right ureter) * Pancreas * Perirenal (perinephric) fat (via kidney) * Prostate (ureter) * Spleen (from left renal pelvis or left ureter) * Uterus (ureter) Further contiguous extension D
800 No evidence of primary tumor U
999 Unknown; extension not stated Primary tumor cannot be assessed Not documented in medical record Death Certificate Only U
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998 (2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001. (3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05**. American Joint Committee on Cancer (Chicago, IL) (4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017 (5) McKiernan, J.M., Hansel, D.E., Stadler, W.M., et al. **Renal Pelvis and Ureter**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017