EOD Regional Nodes V9

Notes

**Note 1:** **Regional nodes and nodes, NOS** * Code only regional nodes and nodes, NOS, in this field. * Distant nodes are coded in EOD Mets. **Note 2:** **Mediastinal and Subcarinal Lymph Nodes** * For codes **400-500**, EOD Regional Nodes is based on the number of mediastinal/subcarinal nodal stations (2-9) are involved. * **There are 14 Nodal Stations based on the [IASLC mapping] (https://www.frontiersin.org/files/Articles/580203/fsurg-07-580203-HTML/image_m/fsurg-07-580203-g001.jpg)**. * Of those 14 Nodal Stations, **8 of them are for mediastinal, including 1 for subcarinal**. **Upper Zone** **Superior mediastinal nodes (Stations 2-4)** * 2R, 2L: Upper paratracheal nodes (Carinal (tracheobronchial) (tracheal bifurcation), Precarinal) * 2R: Right upper paratracheal nodes * 2L: Left upper paratracheal nodes * Includes pericardial lymph nodes * 3a: Prevascular * Anterior mediastinal lymph nodes * Pretracheal, NOS * 3p: Retrotracheal * Posterior lymph nodes (tracheoesophageal) * 4R, 4L: Lower paratracheal nodes (includes Azygos) * 4R: Right lower paratracheal nodes * 4L: Left lower paratracheal nodes **AP Zone** **Aortic nodes (Stations 5-6)** * 5: Subaortic * Aortic-pulmonary window * 6: Para-aortic * Ascending aorta (phrenic) * Aortic (above diaphragm), NOS * Peri/para-aortic, NOS **Inferior mediastinal nodes (Nodal stations 7-9)** **Subcarinal Zone (Station 7)** **Lower Zone (Stations 8-9)** * 8: Paraesophageal, periesophageal * 9: Pulmonary ligament **Note 3:** **"Vocal cord paralysis" or "Superior vena cava syndrome"** * "Vocal cord paralysis," "superior vena cava syndrome," and "compression of the trachea or the esophagus" are classified as either direct extension from the primary tumor or mediastinal lymph node involvement * **Caused by direct extension of the primary tumor** * Code as primary tumor involvement (EOD Primary Tumor, code 650) * **Primary tumor is peripheral and clearly unrelated to vocal cord paralysis, SVC obstruction, or compression of the trachea, or the esophagus** * These manifestations are secondary to lymph node involvement; code as mediastinal lymph node involvement (EOD Lymph Nodes, code 400, 450 or 500, depending on the number of involved mediastinal lymph nodes) * **Unable to determine if manifestations due to direct extension or mediastinal lymph node involvement** * Record as mediastinal lymph node involvement (EOD Lymph Nodes, code 400, 450 or 500, depending on the number of involved mediastinal lymph nodes) **Note 4:** **Lymph nodes, NOS** * Code 800 if regional lymph nodes are involved, but there is no indication which ones are involved.
Code Description SS2018 N
000 No regional lymph node involvement NONE
300 IPSILATERAL NODES ONLY (HILAR) (Stations 10-14) * See code 700 for contralateral or bilateral nodes Hilar/Interlobar Zone, (Stations 10-11) * Hilar (Station 10R, 10L) * Bronchial (peri/parabronchial) * Bronchopulmonary * Proximal lobar * Pulmonary root * Interlobar (Station 11R, 11L) Peripheral Zone, (Stations 12-14) - Lobar (Station 12R, 12L) - Segmental (Station 13R, 13L) - Subsegmental (Station 14R, 14L) RN
400 IPSILATERAL NODES ONLY (SUBCARINAL OR MEDIASTINAL, Stations 2-9) * See code 700 for contralateral or bilateral nodes (Stations 2 and 4 only) Subcarinal nodes (Station 7) involved ONLY OR One Mediastinal Station involved WITH or WITHOUT Subcarinal nodes (Station 7) * Other mediastinal nodal stations include: 2R, 2l, 3a, 3p, 4R, 4L, 5, 6, 8, 9 RN
450 IPSILATERAL NODES ONLY (SUBCARINAL OR MEDIASTINAL, Stations 2-9) * See code 700 for contralateral or bilateral nodes (Stations 2 and 4 only) Two or more mediastinal nodal stations involved WITH or WITHOUT Subcarinal lymph nodes (Station 7) * Other mediastinal nodal stations include: 2R, 2l, 3a, 3p, 4R, 4L, 5, 6, 8, 9 RN
500 IPSILATERAL NODES ONLY (SUBCARINAL OR MEDIASTINAL, Stations 2-9) * See code 700 for contralateral or bilateral nodes (Stations 2 and 4 only) Mediastinal nodal stations involved, unknown how many WITH or WITHOUT involvement of subcarinal nodes * Other mediastinal nodal stations include: 2R, 2l, 3a, 3p, 4R, 4L, 5, 6, 8, 9 Mediastinal nodes, NOS RN
600 IPSILATERAL or CONTRALATERAL Supraclavicular Zone (Station 1) * Low cervical * Proximal root * Scalene (inferior deep cervical) * Sternal notch * Supraclavicular (transverse cervical) D
700 CONTRALATERAL OR BILATERAL * Hilar (Station 10R, 10L) * Bronchial (peri/parabronchial) * Bronchopulmonary * Proximal lobar * Pulmonary root * Interlobar (Station 11R, 11L) Peripheral Zone, (Stations 12-14) - Lobar (Station 12R, 12L) - Segmental (Station 13R, 13L) - Subsegmental (Station 14R, 14L) Superior mediastinal + Paratracheal (left, right, upper, low, NOS) - Azygos (lower paratracheal) (4R, 4L) - Upper paratracheal (2R, 2L) D
800 Regional lymph node(s), NOS Lymph node(s), NOS RN
999 Unknown; regional lymph node(s) not stated Regional lymph node(s) cannot be assessed Not documented in medical record Death Certificate Only U
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998 (2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001. (3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05**. American Joint Committee on Cancer (Chicago, IL) (4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017 (5) **Lung**, from the AJCC Cancer Staging System Version 9 (2025). Used with permission of the American College of Surgeons, Chicago, Illinois.