EOD Regional Nodes
Notes
**Note 1:** **Regional nodes and nodes, NOS**
* Code only regional nodes and nodes, NOS, in this field. Distant nodes are coded in EOD Mets.
**Note 2:** **Inguinal lymph nodes**
* Inguinal lymph nodes are no longer coded as regional lymph nodes. See EOD Mets.
**Note 3:** **Isolated tumor cells**
* Isolated tumor cells (ITCs) are defined as single tumor cells or small clusters not greater than 0.2 mm, usually detected by immunohistochemical (IHC) or molecular methods.
* ITCs do not usually show evidence of malignant activity (e.g., proliferation or stromal reaction). Lymph nodes with ITCs only are not counted as positive nodes
* For positive ITCs with NO regional lymph node involvement, code 050
**Note 4:** **Regional lymph nodes include (bilateral and contralateral)**
- Intrabdominal
- Para-aortic, NOS
+ Aortic
+ Lateral aortic/lateral lumbar
+ Periaortic
- Pelvic, NOS
+ Iliac, NOS
+ Common
+ External
+ Internal (hypogastric) (obturator)
+ Paracervical
+ Parametrial
+ Sacral, NOS
+ Lateral (laterosacral)
+ Middle (promontorial) (Gerota's node)
+ Presacral
+ Uterosacral
- Retroperitoneal, NOS
**Note 5:** **Lymph nodes, NOS**
* Code 800 if regional lymph nodes are involved, but there is no indication which ones are involved.
| Code |
Description |
SS2018 N |
| 000 |
No regional lymph node involvement |
NONE |
| 050 |
Isolated tumors cells no greater than 0.2 mm |
NONE |
| 300 |
Lymph node metastasis less than or equal to 10 mm
FIGO Stage IIIA1i |
RN |
| 400 |
Lymph node metastasis greater than 10 mm
FIGO Stage IIIA1ii |
RN |
| 500 |
Lymph node metastasis, size unknown
FIGO Stage IIIAI |
RN |
| 800 |
Regional lymph node(s), NOS
Lymph node(s), NOS |
RN |
| 999 |
Unknown; regional lymph node(s) not stated
Regional lymph node(s) cannot be assessed
Not documented in medical record
Death Certificate Only |
U |
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998
(2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001.
(3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05**. American Joint Committee on Cancer (Chicago, IL)
(4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017
(5) **Introduction to Female Reproductive Organs**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017
(6) Prat, J., Olawaiye, A.B., Mutch, D.G., et al. **Ovary, Fallopian Tube, and Primary Peritoneal Carcinoma**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017
