EOD Primary Tumor

Notes

**Note 1:** Code 000 (behavior code 2) includes cancer cells confined within the glandular basement membrane (intraepithelial), or described as in situ. **Note 2:** Code 050 (behavior code 3) includes the following: * Intramucosal, NOS * Lamina propria * Mucosa, NOS * Confined to, but not through the muscularis mucosa **Note 3:** Ignore intraluminal extension to adjacent segment(s) of colon/rectum or to the ileum from the cecum; code depth of invasion or extracolonic spread as indicated. **Note 4:** Tumor that is adherent to other organs or structures, macroscopically, is coded as 600 or 700. However, if no tumor is present in the adhesion, microscopically, the classification should be coded to 100-500. **Note 5:** Invasion into "pericolonic/pericolorectal tissue" can be either codes 300 or 400, depending on the primary site. Some sites are entirely peritonealized; some sites are only partially peritonealized or have no peritoneum. Code 300 may not be used for sites that are entirely peritonealized (cecum, transverse colon, sigmoid colon, rectosigmoid colon, upper third of rectum). + Code 300 - Invasion through muscularis propria or muscularis, NOS - Non-peritonealized pericolic/perirectal tissues invaded [Ascending Colon/Descending Colon/Hepatic Flexure/Splenic Flexure/Upper two thirds of rectum: Posterior surface; Lower third of rectum] - Subserosal tissue/(sub)serosal fat invaded + Code 400 - Mesentery - Peritonealized pericolic/perirectal tissues invaded [Ascending Colon/Descending Colon/Hepatic Flexure/Splenic Flexure/Upper third of rectum: anterior and lateral surfaces; Cecum; Sigmoid Colon; Transverse Colon; Rectosigmoid; Rectum: middle third anterior surface] - Pericolic/Perirectal fat + If the pathologist does not further describe the “pericolic/perirectal tissues” as either “non-peritonealized pericolic/perirectal tissues” vs “peritonealized pericolic/perirectal tissues” and the gross description does not describe the tumor relation to the serosa/peritoneal surface, and it cannot be determined whether the tumor arises in a peritonealized portion of the colon, code 300. **Note 6:** Tumors characterized by involvement of the serosal surface (visceral peritoneum) by direct extension or perforation in which the tumor cells are continuous with the serosal surface through inflammation are coded to 500.
Code Description SS2018 T
000 In situ: Noninvasive; intraepithelial (Adeno)carcinoma in a polyp or adenoma, noninvasive IS
050 Intramucosal, NOS Lamina propria Mucosa, NOS Confined to, but not through muscularis mucosa L
100 Submucosa (superficial invasion) - Rectum: WITH or WITHOUT intraluminal extension to colon and/or anal canal/anus Through the muscularis mucosa but not into the muscularis propria Confined to polyp (head, stalk, NOS) Confined to colon, rectum, rectosigmoid, NOS Localized, NOS L
200 Muscularis propria invaded - Rectum: WITH or WITHOUT intraluminal extension to colon and/or anal canal/anus L
300 Extension through wall, NOS Invasion through muscularis propria or muscularis, NOS - Rectum: WITH or WITHOUT intraluminal extension to colon and/or anal canal/anus Non-peritonealized pericolic/perirectal tissues invaded (see Code 400 for peritonealized pericolic/perirectal tissues invaded. See Note 5) Pericolic/perirectal tissues invaded, NOS (unknown whether non-peritonealized or peritonealized. See Note 5) Perimuscular tissue invaded Subserosal tissue/(sub)serosal fat invaded Transmural, NOS Wall, NOS L
400 Adjacent (connective) tissue(s), NOS Fat, NOS Gastrocolic ligament (transverse colon and flexures) Greater omentum (transverse colon and flexures) Mesentery (including mesenteric fat, mesocolon) Pericolic fat Perirectal fat Peritonealized pericolic/perirectal tissues invaded (see code 300 for non-peritonealized pericolic/perirectal tissues invaded. See Note 5) Rectovaginal septum (rectum) Retroperitoneal fat (ascending and descending colon only) RE
500 Mesothelium Serosa Tunica serosa Invasion of/through the visceral peritoneum RE
600 Adherent to other organs or structures clinically with no microscopic examination Tumor found in adhesion(s) if microscopic examination performed All Colon subsites - Abdominal wall - Retroperitoneum (excluding fat) - Small intestine Cecum (C180) - Greater omentum Ascending colon (C182) - Greater omentum - Kidney, right - Liver, right lobe - Ureter, right Transverse colon and flexures (C183, C184, C185) - Bile ducts - Gallbladder - Kidney - Liver - Pancreas - Spleen - Stomach Descending colon (C186) - Greater omentum - Kidney, left - Pelvic wall - Spleen - Ureter, left Sigmoid colon (C187) - Greater omentum - Pelvic wall Rectosigmoid (C199) - Cul de sac (rectouterine pouch) - Pelvic wall/pelvic plexuses - Small intestine Rectum (C209) - Anus/anal canal - Bladder (males only) - Cul de sac (rectouterine pouch) - Ductus deferens - Pelvic wall - Prostate - Rectovaginal septum - Rectovesical fascia (males only) - Seminal vesicle(s) - Skeletal muscles of pelvic floor - Vagina RE
700 All Colon subsites - Adrenal (suprarenal) gland - Bladder - Diaphragm - Fallopian tube - Fistula to skin - Gallbladder (except Transverse Colon and Flexures, see code 600) - Other segment(s) of colon via serosa - Ovary(ies) - Uterus Cecum (C180) - Kidney - Liver - Ureter Transverse colon and flexures - Ureter Sigmoid colon - Cul de sac (rectouterine pouch) - Ureter Rectosigmoid - Bladder - Colon via serosa - Fallopian tube(s) - Ovary(ies) - Prostate - Skeletal muscles of pelvic floor - Ureter(s) - Vagina Rectum - Bladder (females only) - Bone(s) of pelvis - Cervix - Perineum, perianal skin - Sacrum - Sacral plexus - Urethra Further contiguous extension D
800 No evidence of primary tumor U
999 Unknown; extension not stated Primary tumor cannot be assessed Not documented in medical record Death Certificate Only U
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