EOD Regional Nodes
Notes
**Note 1:** Code only regional nodes and nodes, NOS, in this field. Distant nodes are coded in EOD Mets.
**Note 2:** Isolated tumor cells (ITCs) are defined as single tumor cells or small clusters not greater than 0.2 mm, usually detected by immunohistochemical (IHC) or molecular methods. ITCs do not usually show evidence of malignant activity (e.g., proliferation or stromal reaction).
* Lymph nodes with isolated tumor cells (ITCs) are counted as positive lymph nodes
**Note 3:** In transit metastasis is defined as a tumor distinct from the primary lesion and located either between the primary lesion and the draining regional lymph node(s) or distal to the primary lesion. In transit metastasis with positive lymph node(s) are coded under regional lymph nodes.
* Code 600 if there are **clinically** in-transit metastasis WITHOUT regional lymph node involvement
* Code 650 if there are **clinically** in-transit metastasis WITH regional lymph node involvement
* Code 700 if there are **pathologically** in-transit metastasis WITHOUT regional lymph node involvement
* Code 750 if there are **pathologically** in-transit metastasis WITH regional lymph node involvement
**Note 4:** Bilateral or contralateral nodes are classified as regional nodes for head, neck, and truncal tumors with bidirectional drainage to primary nodal basins, as shown on lymphoscintigraphy. Truncal tumors may also drain to both cephalad and caudal primary nodal basins as shown on lymphoscintigraphy.
* Clinical assessment of bilateral/contralateral or cephalad/caudal regional nodal involvement is required for tumors where lymphoscintigraphy is not performed
**Note 5:** Contiguous or secondary nodal basins are the next nodal drainage basins beyond the primary nodal basins and are coded as regional nodes.
**Note 6:** Regional lymph nodes for skin
* Single, Multiple, Ipsilateral
- See *EOD Mets* for contralateral or bilateral nodes (except for head and neck skin primaries)
**Head and Neck skin primaries only (C000-C002, C006, C440, C442-C444) (includes bilateral or contralateral nodes)**
- Levels I-VII
- Axillary (neck only, C444)
- Cervical, NOS
- Deep cervical, NOS
- Facial (buccinator, buccal, nasolabial)
- Internal jugular, NOS
- Parapharyngeal
- Parotid (infraauricular, intraparotid, periparotid, preauricular)
- Retroauricular (mastoid)
- Retropharyngeal
- Suboccipital
**Skin of trunk (C445)**
- Upper trunk
+ Axillary
+ Cervical
+ Internal mammary
+ Supraclavicular
- Lower trunk
+ Superficial inguinal (femoral)
**Skin of upper limb and shoulder (C446)**
- Axillary
- Cervical
- Epitrochlear for hand/forearm
- Internal mammary (parasternal)
- Spinal accessory for shoulder
- Supraclavicular (transverse cervical)
**Skin of lower limb and hip (C447)**
- Femoral (superficial inguinal)
- Inguinal
- Popliteal for heel and calf
**Vulva (C510-C512, C518-C519)**
- Deep inguinal, NOS
- Femoral
- Inguinal, NOS
- Inguinofemoral (groin)
- Node of Cloquet or Rosenmuller (highest deep inguinal)
- Superficial inguinal (femoral)
**Penis (C600-C602, C608-C609)**
- Iliac, NOS
+ External
+ Internal (hypogastric, obturator)
- Inguinal, NOS
+ Node of Cloquet or Rosenmuller (highest deep inguinal)
+ Superficial [femoral]
- Pelvic, NOS
**Scrotum (C632)**
- Iliac, NOS
+ External
+ Internal (hypogastric), NOS
* Obturator
- Inguinal, NOS
+ Deep inguinal, NOS
* Node of Cloquet or Rosenmuller (highest deep inguinal)
+ Superficial inguinal (femoral)
Code |
Description |
SS2018 N |
000 |
No regional lymph node metastasis detected on clinical
AND/OR radiologic examination, (sentinel node) biopsy or lymph node dissection |
NONE |
100 |
CLINICAL ONLY
Clinical and/or radiologic exam positive nodes
- WITHOUT biopsy or resection of lymph nodes |
RN |
200 |
CLINICAL ONLY
Clinically positive nodes on core biopsy/FNA
- WITHOUT sentinel lymph node biopsy or resection of lymph nodes |
RN |
300 |
PATHOLOGICAL ONLY
Clinically occult nodes
- WITH positive nodes from sentinel node biopsy |
RN |
350 |
PATHOLOGICAL ONLY
Clinically occult nodes
- WITH positive nodes on lymph node resection |
RN |
400 |
PATHOLOGICAL ONLY
Clinically and/or radiologically positive nodes
- WITH positive nodes on biopsy or lymph node resection |
RN |
500 |
PATHOLOGICAL ONLY
Clinically unknown if positive or negative
- WITH positive nodes on biopsy or lymph node resection |
RN |
600 |
CLINICAL ONLY
In-transit metastasis present
- WITHOUT lymph node metastasis or UNKNOWN
Discontinuous from primary tumor
Located between primary tumor and draining regional nodal basin
OR distal to the primary tumor |
RN |
650 |
CLINICAL ONLY
Code 600 WITH lymph node metastasis |
RN |
700 |
PATHOLOGICAL ONLY
In-transit metastasis present
- WITHOUT lymph node metastasis or UNKNOWN
Discontinuous from primary tumor
Located between primary tumor and draining regional nodal basin
OR distal to the primary tumor |
RN |
750 |
PATHOLOGICAL ONLY
Code 700 WITH lymph node metastasis |
RN |
800 |
Regional lymph node(s), NOS
Lymph node(s), NOS |
RN |
999 |
Unknown; regional lymph node(s) not stated
Regional lymph node(s) cannot be assessed
Not documented in patient record
Death Certificate Only |
U |
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