EOD Primary Tumor
Notes
**Note 1:** Periosteum is a fibrous membrane that wraps the outer surface of bones. Cortical bone is the dense compact outer layer of the bone. Trabecular, cancellous, or spongy bone (spongiosa) is a porous network of tissue filling the interior of bone, decreasing weight and allowing room for blood vessels and marrow.
**Note 2:** For codes 100-500, the derived EOD T is based on depth of invasion (DOI) in conjunction with size. In addition, some of the anatomical structures listed are localized for Summary Stage 2018 while others are regional for Summary Stage 2018. The anatomical structures are divided into two groups: Group 1 is for localized tumors, while Group 2 is for regional tumor.
**Group 1 extension WITH any size tumor: Use the following for codes 100, 150, 200**
- Invasive tumor confined to lamina propria (mucoperiosteum) (stroma)
- Confined to gum, NOS
- Localized, NOS
**Group 2 extension WITH any size tumor: Use the following for codes 300, 400, 500**
- Bone, NOS
+ Bone (mandible, maxilla, palatine)
+ Cartilage (mandible, maxilla, NOS)
+ Cortical bone, invasion of (mandible, maxilla, NOS)
- Buccal mucosa (inner cheek)
- Facial muscle, NOS
- Floor of mouth
- Hard palate (includes cortical palatine bone)
- Labial mucosa (inner lip)
- Lateral pharyngeal wall
- Lip, NOS
- Soft palate including uvula
- Subcutaneous soft tissue of face
- Tongue mucosa
- Tonsillar pillars and fossae
- Tonsils
**Note 3:** Once the correct group is determined, the codes are then determined based on the depth of invasion.
- Depth of invasion less than or equal to 5 mm or UNKNOWN depth of invasion (codes 100, 300)
- Depth of invasion greater than 5 mm to less than or equal to 10 mm (codes 150, 400)
- Depth of invasion greater than 10 mm (codes 200, 500)
**Note 4:** Involvement through cortical bone is required for assignment of code 600.
- Code 300, 400, or 500 (depending on the depth of invasion) when the tumor is limited to the cortical bone/cortex of the mandible or maxilla. Invasion of the bone, NOS (mandible, NOS or maxilla, NOS) is **not** equivalent to invasion through the cortical bone (code 600).
| Code |
Description |
SS2018 T |
| 000 |
In situ, intraepithelial, noninvasive |
IS |
| 100 |
Group 1 WITH depth of invasion (DOI) less than or equal to 5 mm
OR unknown depth of invasion |
L |
| 150 |
Group 1 WITH depth of invasion (DOI) greater than 5 mm and less than or equal to 10 mm |
L |
| 200 |
Group 1 WITH depth of invasion (DOI) greater than 10 mm |
L |
| 300 |
Group 2 WITH depth of invasion (DOI) less than or equal to 5 mm
OR unknown depth of invasion |
RE |
| 400 |
Group 2 WITH depth of invasion (DOI) greater than 5 mm and less than or equal to 10 mm |
RE |
| 500 |
Group 2 WITH depth of invasion (DOI) greater than 10 mm |
RE |
| 600 |
Invasion through cortical bone (mandible, maxilla, NOS)
Deep (extrinsic) muscle of tongue
- Genioglossus
- Hyoglossus
- Palatoglossus
- Styloglossus
Tongue muscle (intrinsic)
Trabecular bone (mandible, maxilla, palatine, NOS) |
RE |
| 650 |
Maxillary sinus/antrum
Nasal cavity
Nose
Skin of face |
D |
| 700 |
Internal carotid artery (encased)
Masticator space
Pterygoid plates
Skull base
Specified bone (other than mandible, maxilla, palatine)
Further contiguous extension |
D |
| 999 |
Unknown; extension not stated
Primary tumor cannot be assessed
Not documented in patient record
Death Certificate Only |
U |
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998
(2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001.
(3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05**. American Joint Committee on Cancer (Chicago, IL)
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