EOD Regional Nodes
Notes
**Note 1:** Code only regional nodes and nodes, NOS, in this field. Distant nodes are coded in EOD Mets.
**Note 2:** Lymph nodes with isolated tumor cells (ITCs) are counted as positive lymph nodes. ITCs are defined as any tumor deposits in lymph nodes less than or equal to 0.2 mm.
**Note 3:** Code 300 if there are satellite(s) or in-transit metastasis without regional lymph node involvement. Code 500 or 700 (based on number of nodes involved) if both satellite nodules/in-transit metastases and regional lymph nodes are present.
**Note 4:** Bilateral or contralateral nodes are classified as regional nodes for head, neck, and truncal tumors with bidirectional drainage to primary nodal basins, as shown on lymphoscintigraphy. Truncal tumors may also drain to both cephalad and caudal primary nodal basins as shown on lymphoscintigraphy.
* Clinical assessment of bilateral/contralateral or cephalad/caudal regional nodal involvement is required for tumors where lymphoscintigraphy is not performed
**Note 5:** Contiguous or secondary nodal basins are the next nodal drainage basins beyond the primary nodal basins and are coded as regional nodes.
**Note 6:** Regional lymph nodes for skin
* Single, Multiple, Ipsilateral, Bilateral or Contralateral lymph nodes
**Skin of head and neck (C000-C002, C006, C440-C444)**
- Levels I-VII
- Axillary (neck only, C444)
- Cervical, NOS
- Deep cervical, NOS
- Facial (buccinator, buccal, nasolabial)
- Internal jugular, NOS
- Parapharyngeal
- Parotid (infraauricular, intraparotid, periparotid, preauricular)
- Retroauricular (mastoid)
- Retropharyngeal
- Suboccipital
**Skin of upper limb and shoulder (C446)**
- Axillary
- Cervical
- Epitrochlear for hand/forearm
- Internal mammary (parasternal)
- Spinal accessory for shoulder
- Supraclavicular (transverse cervical)
**Skin of lower limb and hip (C447)**
- Femoral (superficial inguinal)
- Popliteal for heel and calf
**Vulva (C510-C512, C518-C519)**
- Deep inguinal, NOS
- Femoral
- Inguinal, NOS
- Inguinofemoral (groin)
- Node of Cloquet or Rosenmuller (highest deep inguinal)
- Superficial inguinal (femoral)
**Penis (C600-C602, C608-C609)**
- Iliac, NOS
+ External
+ Internal (hypogastric, obturator)
- Inguinal, NOS
+ Node of Cloquet or Rosenmuller (highest deep inguinal)
+ Superficial [femoral]
- Pelvic, NOS
**Scrotum (C632)**
- Iliac, NOS
+ External
+ Internal (hypogastric), NOS
* Obturator
- Inguinal, NOS
+ Deep inguinal, NOS
* Node of Cloquet or Rosenmuller (highest deep inguinal)
+ Superficial inguinal (femoral)
**Note 7:** See the schema specific anatomical sites for the list of specific regional nodes.
- C210 Anus
- C500 Breast
| Code |
Description |
SS2018 N |
| 000 |
No regional lymph node involvement |
NONE |
| 100 |
One clinically occult (detected by SLN biopsy)
- WITHOUT in-transit, satellite, and/or microsatellite metastasis |
RN |
| 200 |
One clinically detected node
- WITHOUT in-transit, satellite, and/or microsatellite metastasis |
RN |
| 300 |
No clinically occult or detected nodes
- WITH in-transit, satellite, and/or microsatellite metastasis
+ WITH or WITHOUT involved lymph nodes |
RN |
| 350 |
One involved node UNKNOWN how detected
- WITHOUT in-transit, satellite, and/or microsatellite metastasis |
RN |
| 400 |
Two or three clinically occult (detected by SLN biopsy)
- WITHOUT in-transit, satellite, and/or microsatellite metastasis |
RN |
| 450 |
Two or three involved nodes WITH 1 or greater clinically detected
- WITHOUT in-transit, satellite, and/or microsatellite metastasis |
RN |
| 500 |
One clinically occult or detected node
- WITH in-transit, satellite, and/or microsatellite metastasis |
RN |
| 550 |
Two or three involved nodes UNKNOWN how detected
- WITHOUT in-transit, satellite, and/or microsatellite metastasis |
RN |
| 600 |
Four or more clinically occult (detected by SLN biopsy)
- WITHOUT in-transit, satellite, and/or microsatellite metastasis |
RN |
| 650 |
Four or more positive WITH 1 or greater clinically detected
- AND/OR matted nodes
+ WITHOUT in-transit, satellite, and/or microsatellite metastasis |
RN |
| 700 |
Two or more clinically occult or detected
- AND/OR matted nodes
+ WITH in-transit, satellite, and/or microsatellite metastasis |
RN |
| 750 |
Four or more involved nodes UNKNOWN how detected
- UNKNOWN if matted nodes
+ WITHOUT in-transit, satellite, and/or microsatellite metastasis |
RN |
| 800 |
Regional lymph node(s), NOS
Lymph node(s), NOS |
RN |
| 999 |
Unknown; regional lymph node(s) not stated
Regional lymph node(s) cannot be assessed
Not documented in patient record
Death Certificate Only |
U |
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998
(2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001.
(3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05**. American Joint Committee on Cancer (Chicago, IL)
(4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 3-30
(5) Gershenwald, J.E., Scolyer, R.A., et al. **Melanoma of the Skin**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 563-585
