EOD Primary Tumor


**Note 1:** Multiple tumors include satellitosis, multifocal tumors, and intrahepatic metastasis. **Note 2:** Intrahepatic vascular invasion (codes 200 and 300) includes the following * Major hepatic vessel invasion * First and second-order branches of the portal veins or hepatic arteries * Hepatic veins (right, middle, or left) * Microscopic invasion of smaller intraparenchymal vascular structures (identified on histopathological examination)
Code Description SS2018 T
000 In situ, intraepithelial, noninvasive Intraductal tumor Biliary intraepithelial neoplasia grade 3 (BiIIN-3) IS
100 Any size tumor Solitary tumor WITHOUT or UNKNOWN intrahepatic vascular invasion Confined to intrahepatic bile duct, NOS Localized, NOS L
200 Code 100 WITH intrahepatic vascular invasion L
300 Multiple tumors WITH or WITHOUT intrahepatic vascular invasion L
500 Invasion beyond visceral peritoneum into adjacent connective tissues WITHOUT invasion of extrahepatic structures/organs RE
600 Extrahepatic bile ducts PLUS satellite nodules in more than one lobe OR multiple tumors with extrahepatic major vascular invasion Abdominal wall Colon Common bile duct Diaphragm Duodenum Extrahepatic structures, NOS - Retrohepatic vena cava - Vena cava Hepatic artery (proper) Gallbladder Lesser omentum Ligament(s) - Coronary - Falciform - Hepatoduodenal - Hepatogastric - Round (of liver) - Triangular Peritoneum (parietal, NOS) Retrohepatic vena cava RE
700 Multiple (satellite) nodules on surface of liver parenchyma Pancreas Pleura Stomach Further contiguous extension D
800 No evidence of primary tumor U
999 Unknown; extension not stated Primary tumor cannot be assessed Not documented in patient record Death Certificate Only U
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998 (2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001. (3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05**. American Joint Committee on Cancer (Chicago, IL) (4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 3-30 (5) Aloia, T., Pawlik, T.M., Vauthey, J.N., et al. **Intrahepatic Bile Ducts**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 295-302