EOD Primary Tumor

Notes

**Note 1:** If both eyes are involved, code the information for the most extensively involved eye in this field. **Note 2:** Pathological staging information from an enucleation always takes precedence over clinical staging, except in cases with neoadjuvant treatment where clinical disease is as extensive as or more extensive than disease at surgery.
Code Description SS2018 T
100 CLINICAL diagnosis only Intraretinal tumor(s) with subretinal fluid - Equal to but not greater than 3 millimeter (mm) - AND Location not closer than 1.5 mm to optic disk or fovea L
125 CLINICAL diagnosis only Intraretinal tumor(s) with subretinal fluid - Greater than 3 millimeter (mm) - AND Location closer than 1.5 mm from disc or fovea L
150 CLINICAL diagnosis only Intraretinal tumor(s) with subretinal fluid ≤5 mm from the base of any tumor Tumor confined to retina, NOS Localized, NOS L
175 PATHOLOGICAL diagnosis only Intraocular tumor(s) WITHOUT any - Local invasion - Focal choroidal invasion - Pre- or intralaminar involvement of the optic nerve head Tumor confined to retina, NOS Localized, NOS L
200 CLINICAL diagnosis only Intraocular tumor(s) WITH - Subretinal fluid greater than 5 mm [0.5 cm] from base of tumor - WITH or WITHOUT retinal detachment L
225 CLINICAL diagnosis only Intraocular tumor(s) WITH - Vitreous seeding and/or subretinal seeding - WITH or WITHOUT retinal detachment L
250 PATHOLOGICAL diagnosis only Intraocular tumor(s) WITH local invasion - Concomitant focal choroidal invasion - AND pre- or intralaminar involvement of optic nerve head L
275 PATHOLOGICAL diagnosis only Intraocular tumor(s) WITH local invasion Stromal invasion iris - AND/OR trabecular meshwork - AND/OR Schlemm’s canal L
300 CLINICAL or PATHOLOGICAL Intraocular tumor(s) WITH local invasion, NOS Intraocular tumor(s) with retinal detachment, vitreous seeding, or subretinal seeding, NOS L
325 CLINICAL diagnosis only Advanced intraocular tumor(s) WITH - Phthisis or pre-phthisis bulbi L
350 PATHOLOGICAL diagnosis only Intraocular tumor(s) WITH significant local invasion - Massive choroidal invasion (greater than 3 mm [0.3 cm] in largest diameter) - OR multiple foci or focal choroidal involvement (greater than 3 mm) - OR full-thickness choroidal involvement L
375 CLINICAL diagnosis only Advanced intraocular tumor(s) WITH invasion of - Anterior chamber - Choroid - Ciliary body - Iris - Lens - Pars plana - Zonules L
400 PATHOLOGICAL diagnosis only Intraocular tumor(s) WITH significant local invasion - Retrolaminar invasion of optic nerve head - NOT involving transected end of optic nerve L
425 CLINICAL diagnosis only Advanced intraocular tumor(s) WITH - Raised intraocular pressure with neovascularization - AND/OR buphthalmos L
450 PATHOLOGICAL diagnosis only Intraocular tumor(s) WITH significant local invasion - Any partial-thickness involvement of sclera within inner two thirds L
475 CLINICAL diagnosis only Advanced intraocular tumor(s) WITH - Hyphema AND/OR massive vitreous hemorrhage L
500 PATHOLOGICAL diagnosis only Advanced intraocular tumor(s) WITH - Full-thickness invasion into outer third of sclera - AND/OR invasion into or around emissary channels L
525 CLINICAL diagnosis only Advanced intraocular tumor(s) WITH - Aseptic orbital cellulitis L
550 CLINICAL OR PATHOLOGICAL Advanced intraocular tumor(s) WITH significant local invasion L
600 CLINICAL diagnosis only Extraocular tumor(s) involving orbit - Radiologic evidence of retrobulbar optic nerve involvement - OR thickening of optic nerve and/or orbital tissues RE
650 CLINICAL diagnosis only Extraocular tumor(s) involving orbit, including optic nerve - WITH proptosis AND/OR an orbital mass RE
700 CLINICAL diagnosis only Extraocular tumor(s) involving orbit, including optic nerve, NOS RE
750 PATHOLOGICAL diagnosis only Evidence of extraocular tumor - Tumor at transected end of optic nerve - Tumor in the meningeal spaces around optic nerve Full-thickness invasion of sclera WITH invasion of - Adjacent adipose tissue - Bone - Conjunctiva - Episclera - Extraocular muscle - Eyelids RE
800 No evidence of primary tumor U
999 Unknown; extension not stated Primary tumor cannot be assessed Not documented in patient record Death Certificate Only U
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998 (2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001. (3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05**. American Joint Committee on Cancer (Chicago, IL) (4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 3-30 (5) Mallipatna, A.C., Finger, P.T., et al. **Retinoblastoma**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 819-831