EOD Regional Nodes
Notes
**Note 1:** Code only regional nodes and nodes, NOS, in this field. Distant nodes are coded in EOD Mets.
**Note 2:** Lymph nodes with isolated tumor cells (ITCs) are counted as positive lymph nodes. ITCs are defined as any tumor deposits in lymph nodes less than or equal to 0.2 mm.
**Note 3:** In transit metastasis is defined as a tumor distinct from the primary lesion and located either between the primary lesion and the draining regional lymph node(s) or distal to the primary lesion. In transit metastasis with positive lymph node(s) are coded under regional lymph nodes.
**Note 4:** Regional lymph nodes for skin
* Single, Multiple, Ipsilateral, Bilateral or Contralateral lymph nodes
**Skin of head and neck (C000-C006, C008-C009, C440-C444)**
- Levels I-VII
- Axillary (neck only, C444)
- Cervical, NOS
- Deep cervical, NOS
- Facial (buccinator, buccal, nasolabial)
- Internal jugular, NOS
- Parapharyngeal
- Parotid (infraauricular, intraparotid, periparotid, preauricular)
- Retroauricular (mastoid)
- Retropharyngeal
- Suboccipital
**Skin of upper limb and shoulder (C446)**
- Axillary
- Cervical
- Epitrochlear for hand/forearm
- Internal mammary (parasternal)
- Spinal accessory for shoulder
- Supraclavicular (transverse cervical)
**Skin of lower limb and hip (C447)**
- Femoral (superficial inguinal)
- Popliteal for heel and calf
**Vulva (C510-C512, C518-C519)**
- Deep inguinal, NOS
- Femoral
- Inguinal, NOS
- Inguinofemoral (groin)
- Node of Cloquet or Rosenmuller (highest deep inguinal)
- Superficial inguinal (femoral)
**Penis (C600-C602, C608-C609)**
- Iliac, NOS
+ External
+ Internal (hypogastric, obturator)
- Inguinal, NOS
+ Node of Cloquet or Rosenmuller (highest deep inguinal)
+ Superficial [femoral]
- Pelvic, NOS
**Scrotum (C632)**
- Iliac, NOS
+ External
+ Internal (hypogastric), NOS
* Obturator
- Inguinal, NOS
+ Deep inguinal, NOS
* Node of Cloquet or Rosenmuller (highest deep inguinal)
+ Superficial inguinal (femoral)
| Code |
Description |
SS2018 N |
| 000 |
No regional lymph node metastasis detected on clinical
AND/OR radiologic examination, (sentinel node) biopsy or lymph node dissection |
NONE |
| 100 |
CLINICAL ONLY
Clinical and/or radiologic exam positive nodes
- WITHOUT biopsy or resection of lymph nodes |
RN |
| 200 |
CLINICAL ONLY
Clinically positive nodes on core biopsy/FNA
- WITHOUT sentinel lymph node biopsy or resection of lymph nodes |
RN |
| 300 |
PATHOLOGICAL ONLY
Clinically occult nodes
- WITH positive nodes from sentinel node biopsy |
RN |
| 350 |
PATHOLOGICAL ONLY
Clinically occult nodes
- WITH positive nodes on lymph node resection |
RN |
| 400 |
PATHOLOGICAL ONLY
Clinically and/or radiologically positive nodes
- WITH positive nodes on biopsy or lymph node resection |
RN |
| 500 |
PATHOLOGICAL ONLY
Clinically unknown if positive or negative
- WITH positive nodes on biopsy or lymph node resection |
RN |
| 600 |
CLINICAL ONLY
In-transit metastasis present
- WITHOUT lymph node metastasis or UNKNOWN
Discontinuous from primary tumor
Located between primary tumor and draining regional nodal basin
OR distal to the primary tumor |
RN |
| 650 |
CLINICAL ONLY
Code 600 WITH lymph node metastasis |
RN |
| 700 |
PATHOLOGICAL ONLY
In-transit metastasis present
- WITHOUT lymph node metastasis or UNKNOWN
Discontinuous from primary tumor
Located between primary tumor and draining regional nodal basin
OR distal to the primary tumor |
RN |
| 750 |
PATHOLOGICAL ONLY
Code 700 WITH lymph node metastasis |
RN |
| 800 |
Regional lymph node(s), NOS
Lymph node(s), NOS |
RN |
| 999 |
Unknown; regional lymph node(s) not stated
Regional lymph node(s) cannot be assessed
Not documented in patient record
Death Certificate Only |
U |
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998
(2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001.
(3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05**. American Joint Committee on Cancer (Chicago, IL)
(4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 3-30
(5) Bichakjian, C.K., Nghiem, P., Sober, A.J., et al. **Merkel Cell Carcinoma**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 549-562
