EOD Regional Nodes

Notes

**Note 1:** All lymph node (regional and distant) involvement is coded in this field. * Peripheral nodes (e.g., palpable/accessible nodes) may be used to code this. * Central nodes (code 700) (deep/non-palpable nodes) are only included when they are microscopically proven **Note 2:** Regional node involvement (clinical abnormal peripheral lymph nodes) can be clinically involved despite negative biopsy or a lack of microscopic confirmation. **Note 3:** Dutch grade system includes Grade 1 - Dermatopathic lymphadenopathy (DL) Grade 2 - Early involvement by mycosis fungoides (MF), (presence of cerebriform nuclei larger than 7.5 micrometers (um) Grade 3 - Partial effacement of lymph node architecture; many atypical cerebriform mononuclear cells (CMCs) Grade 4 - Complete effacement of lymph node architecture **Note 4:** National Cancer Institute - Lymph Nodes (NCI LN) grade system includes LN 0 - No atypical lymphocytes LN 1 - Occasional and isolated atypical lymphocytes not arranged in clusters LN 2 - Many atypical lymphocytes or in 3-6 cell clusters LN 3 - Aggregates of atypical lymphocytes; nodal architecture preserved LN 4 - Partial/complete effacement of nodal architecture by atypical lymphocytes or frankly neoplastic cells **Note 5:** A T-cell clone (clone negative or clone positive) is defined by polymerase chain reaction (PCR) or Southern blot analysis of the T-cell receptor gene (TCR).
Code Description SS2018 N
000 No regional lymph node involvement No clinically abnormal peripheral lymph nodes, no biopsy required NONE
050 Clinically enlarged palpable peripheral lymph node(s) (adenopathy) - WITH pathologically negative nodes OR - WITHOUT histologic confirmation RN
100 Clinically abnormal peripheral lymph nodes - Pathologically Dutch grade 1 or NCI LN 0-2 - Clone negative RN
200 Clinically abnormal peripheral lymph nodes - Pathologically Dutch grade 1 or NCI LN 0-2 - Clone positive RN
300 Clinically abnormal peripheral lymph nodes - Pathologically Dutch grade 1 or NCI LN 0-2 - Clone unknown OR Dutch grade and NCI LN grade unknown - Clone positive, negative, or unknown RN
400 Clinically abnormal peripheral lymph nodes - Pathologically Dutch grade 2 or NCI LN 3 - Clone negative RN
500 Clinically abnormal peripheral lymph nodes - Pathologically Dutch grade 2 or NCI LN 3 - Clone positive RN
600 Clinically abnormal peripheral lymph nodes - Pathologically Dutch grade 2 or NCI LN 3 - Clone unknown RN
700 Clinically abnormal peripheral lymph nodes - Pathologically Dutch grades 3-4 or NCI LN 4 - Clone positive or negative or unknown Central nodes - Pathologically Dutch grades 3-4 or NCI LN 4 - Clone positive, negative, or unknown RN
800 Regional lymph node(s), NOS Lymph node(s), NOS Distant lymph node(s), NOS RN
999 Unknown; regional lymph node(s) not stated Regional lymph node(s) cannot be assessed Not documented in patient record Death Certificate Only U
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