Brain – V9: 2023+

Primary Site Histology Behavior Year of Diagnosis
C700, C710-C719 8000-8803, 8810-8858, 8860-8900, 8902-8905, 8921, 8932-8934, 8940-8990, 8992, 9000-9016, 9030-9043, 9045-9221, 9230, 9240-9361, 9363-9365, 9370-9460, 9480-9500, 9505-9507, 9509-9580, 9582, 9671, 9680, 9690, 9699, 9702-9715, 9719, 9749, 9751-9759, 9766 <Any value> 2023-9998, 9999, <BLANK>
C700, C710-C719 8804-8806, 8859, 8901, 8910-8920, 8930-8931, 8935-8936, 8991, 9020, 9044, 9222, 9231, 9366-9368, 9581, 9590-9663, 9673-9679, 9687-9689, 9691-9698, 9700-9701, 9716-9718, 9724-9742, 9761-9765, 9767-9993 0, 1 2023-9998, 9999, <BLANK>

Notes

**Any behavior:** * 8000-8803, 8810-8858, 8860-8900, 8902-8905, 8921, 8932-8934, 8940-8990, 8992, 9000-9016, 9030-9043, 9045-9221, 9230, 9240-9361, 9363-9365, 9370-9460, 9480-9500, 9505-9507, 9509-9580, 9582, 9671, 9680, 9690, 9699, 9702-9715, 9719, 9749, 9751-9759, 9766 **Benign/Borderline histologies (/0, /1):** * 8804-8806, 8859, 8901, 8910-8920, 8930-8931, 8935-8936, 8991, 9020, 9044, 9222, 9231, 9366-9368, 9581, 9590-9663, 9673-9679, 9687-9689, 9691-9698, 9700-9701, 9716-9718, 9724-9742, 9761-9765, 9767-9993 C700 Cerebral meninges C710 Cerebrum C711 Frontal lobe C712 Temporal lobe C713 Parietal lobe C714 Occipital lobe C715 Ventricle, NOS C716 Cerebellum, NOS C717 Brain stem C718 Overlapping lesion of brain C719 Brain, NOS **Note 1:** **Sources used in the development of this schema** * SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998) (https://seer.cancer.gov/archive/manuals/EOD10Dig.3rd.pdf) * SEER Summary Staging Manual-2000: Codes and Coding Instructions (https://seer.cancer.gov/tools/ssm/ssm2000/) * Collaborative Stage Data Collection System, version 02.05: https://cancerstaging.org/cstage/Pages/default.aspx * Brain and Spinal Cord, from the AJCC Cancer Staging System Version 9 (2022). Used with permission of the American College of Surgeons, Chicago, Illinois. **Note 2:** **Other EOD Schemas with Brain sites** * All histologies with behavior /0 and /1 are captured in this schema, for behavior /3, see the following schemas for the listed histologies * **GIST**: 8935-8936 * **Lymphoma**: * 9590, 9596-9663, 9673-9679, 9687-9689, 9691-9698, 9716-9718, 9725-9726, 9735, 9737-9738, 9826-9827: * **Mycosis Fungoides**: 9700-9701 * **Plasma Cell Disorders**: 9731, 9734, 9761 * **Soft Tissue Rare**: 8804-8806, 8859, 8901, 8910-8920, 8930-8931, 8991, 9020, 9044, 9222, 9231, 9366-9368, 9581 **Note 3:** **Medulloblastoma** * For diagnoses January 1, 2023, and forward, the following histologies will be collected in the Medulloblastoma EOD schema * 9362, 9470-9478, 9501-9504, 9508 * *Exception:* For C723 and 9473/3, see Orbital Sarcoma **Note 4:** **Summary Stage** * Summary Stage is the only applicable staging system for this site/histology/schema.

Data Items

Name Default Value Used in Derivation NAACCR Item Required By Metadata
Year of Diagnosis <BLANK> Yes NAACCR #390
dateOfDiagnosis 		None
Primary Site <BLANK> Yes NAACCR #400
primarySite 		None
Histology <BLANK> Yes NAACCR #522
histologicTypeIcdO3 		None
Behavior <BLANK> Yes NAACCR #523
behaviorCodeIcdO3 		None
Tumor Size Clinical <BLANK> No NAACCR #752
tumorSizeClinical 		None
Tumor Size Pathological <BLANK> No NAACCR #754
tumorSizePathologic 		None
Tumor Size Summary 999 No NAACCR #756
tumorSizeSummary 		None
Regional Nodes Positive 99 No NAACCR #820
regionalNodesPositive 		None
Regional Nodes Examined 99 No NAACCR #830
regionalNodesExamined 		None
Neoadjuvant Therapy 9 No NAACCR #1632
neoadjuvantTherapy 		None
Neoadjuvant Therapy – Clinical Response 9 No NAACCR #1633
neoadjuvTherapyClinicalResponse 		None
Neoadjuvant Therapy – Treatment Effect 9 No NAACCR #1634
neoadjuvTherapyTreatmentEffect 		None
EOD Primary Tumor 999 Yes NAACCR #772
eodPrimaryTumor 		None
EOD Regional Nodes 888 Yes NAACCR #774
eodRegionalNodes 		None
EOD Mets 00 Yes NAACCR #776
eodMets 		None
SS2018 <BLANK> No NAACCR #764
summaryStage2018 		None
Grade Clinical 9 Yes NAACCR #3843
gradeClinical 		All SSDI
Grade Pathological 9 Yes NAACCR #3844
gradePathological 		All SSDI
Grade Post Therapy Clin (yc) <BLANK> No NAACCR #1068
gradePostTherapyClin 		COC
NPCR
SEER		 SSDI
Grade Post Therapy Path (yp) <BLANK> No NAACCR #3845
gradePostTherapy 		CCCR/Canada
COC
NPCR
SEER		 SSDI
Brain Molecular Markers 88 No NAACCR #3816
brainMolecularMarkers 		NPCR
SEER		 SSDI
Chromosome 1p Status 8 No NAACCR #3801
chromosome1pLossHeterozygosity 		COC
SEER		 SSDI
Chromosome 19q Status 8 No NAACCR #3802
chromosome19qLossHeterozygosity 		COC
SEER		 SSDI
MGMT 8 No NAACCR #3889
methylationOfO6MGMT 		COC
SEER		 SSDI
Brain Primary Tumor Location <BLANK> No NAACCR #3964
brainPrimaryTumorLocation 		CCCR/Canada 2024–
COC 2024–
NPCR 2024–
SEER 2024–		 SSDI 2024–

Initial Context

Staging Methods

Expand All | Collapse All

Summary Stage 2018

Start

  2. Derived Summary Grade
  3. derived_summary_grade

Next Step

  2. EOD Primary Tumor
  3. ss2018_t

Next Step

  2. EOD Regional Nodes
  3. ss2018_n

Next Step

  2. EOD Mets
  3. ss2018_m

Next Step

  2. Summary Stage Benign
  3. ss2018_derived

End

Outputs

Name Default Value Description NAACCR Item Metadata
Schema ID 09721 NAACCR #3800
schemaId 		None
Derived Version {{ctx_alg_version}} None None
Derived Summary Stage 2018 9 NAACCR #762
derivedSummaryStage2018 		None
Derived Summary Grade 2018 <BLANK> NAACCR #1975
derivedSummaryGrade2018 		None