Brain – V9: 2023+

Primary Site Histology Behavior Year of Diagnosis
C700, C710-C719 8000-8803, 8810-8858, 8860-8900, 8902-8905, 8921, 8932-8934, 8940-8990, 8992, 9000-9016, 9030-9043, 9045-9221, 9230, 9240-9361, 9363-9365, 9370-9460, 9480-9500, 9505-9507, 9509-9580, 9582, 9671, 9680, 9690, 9699, 9702-9715, 9719, 9749, 9751-9759, 9766 <Any value> 2023-9998, 9999, <BLANK>
C700, C710-C719 8804-8806, 8859, 8901, 8910-8920, 8930-8931, 8935-8936, 8991, 9020, 9044, 9222, 9231, 9366-9368, 9581, 9590-9663, 9673-9679, 9687-9689, 9691-9698, 9700-9701, 9716-9718, 9724-9742, 9761-9765, 9767-9993 0, 1 2023-9998, 9999, <BLANK>

Notes

Any behavior:

  • 8000-8803, 8810-8858, 8860-8900, 8902-8905, 8921, 8932-8934, 8940-8990, 8992, 9000-9016, 9030-9043, 9045-9221, 9230, 9240-9361, 9363-9365, 9370-9460, 9480-9500, 9505-9507, 9509-9580, 9582, 9671, 9680, 9690, 9699, 9702-9715, 9719, 9749, 9751-9759, 9766

Benign/Borderline histologies (/0, /1):

  • 8804-8806, 8859, 8901, 8910-8920, 8930-8931, 8935-8936, 8991, 9020, 9044, 9222, 9231, 9366-9368, 9581, 9590-9663, 9673-9679, 9687-9689, 9691-9698, 9700-9701, 9716-9718, 9724-9742, 9761-9765, 9767-9993

C700 Cerebral meninges
C710 Cerebrum
C711 Frontal lobe
C712 Temporal lobe
C713 Parietal lobe
C714 Occipital lobe
C715 Ventricle, NOS
C716 Cerebellum, NOS
C717 Brain stem
C718 Overlapping lesion of brain
C719 Brain, NOS

Note 1: Sources used in the development of this schema

  • SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998) (https://seer.cancer.gov/archive/manuals/EOD10Dig.3rd.pdf)
  • SEER Summary Staging Manual-2000: Codes and Coding Instructions (https://seer.cancer.gov/tools/ssm/ssm2000/)
  • Collaborative Stage Data Collection System, version 02.05: https://cancerstaging.org/cstage/Pages/default.aspx
  • Brain and Spinal Cord, from the AJCC Cancer Staging System Version 9 (2022). Used with permission of the American College of Surgeons, Chicago, Illinois.

Note 2: Other EOD Schemas with Brain sites

  • All histologies with behavior /0 and /1 are captured in this schema, for behavior /3, see the following schemas for the listed histologies
  • GIST: 8935-8936
  • Lymphoma: * 9590, 9596-9663, 9673-9679, 9687-9689, 9691-9698, 9716-9718, 9725-9726, 9735, 9737-9738, 9826-9827:
  • Mycosis Fungoides: 9700-9701
  • Plasma Cell Disorders: 9731, 9734, 9761
  • Soft Tissue Rare: 8804-8806, 8859, 8901, 8910-8920, 8930-8931, 8991, 9020, 9044, 9222, 9231, 9366-9368, 9581

Note 3: Medulloblastoma

  • For diagnoses January 1, 2023, and forward, the following histologies will be collected in the Medulloblastoma EOD schema
    • 9362, 9470-9478, 9501-9504, 9508
    • Exception: For C723 and 9473/3, see Orbital Sarcoma

Note 4: Summary Stage

  • Summary Stage is the only applicable staging system for this site/histology/schema.

Data Items

Name Default Value Used in Derivation NAACCR Item Required By Metadata
Year of Diagnosis <BLANK> Yes NAACCR #390
dateOfDiagnosis
None
Primary Site <BLANK> Yes NAACCR #400
primarySite
None
Histology <BLANK> Yes NAACCR #522
histologicTypeIcdO3
None
Behavior <BLANK> Yes NAACCR #523
behaviorCodeIcdO3
None
Tumor Size Clinical <BLANK> No NAACCR #752
tumorSizeClinical
None
Tumor Size Pathological <BLANK> No NAACCR #754
tumorSizePathologic
None
Tumor Size Summary 999 No NAACCR #756
tumorSizeSummary
None
Regional Nodes Positive 99 No NAACCR #820
regionalNodesPositive
None
Regional Nodes Examined 99 No NAACCR #830
regionalNodesExamined
None
Neoadjuvant Therapy 9 No NAACCR #1632
neoadjuvantTherapy
None
Neoadjuvant Therapy – Clinical Response 9 No NAACCR #1633
neoadjuvTherapyClinicalResponse
None
Neoadjuvant Therapy – Treatment Effect 9 No NAACCR #1634
neoadjuvTherapyTreatmentEffect
None
EOD Primary Tumor 999 Yes NAACCR #772
eodPrimaryTumor
None
EOD Regional Nodes 888 Yes NAACCR #774
eodRegionalNodes
None
EOD Mets 00 Yes NAACCR #776
eodMets
None
SS2018 <BLANK> No NAACCR #764
summaryStage2018
None
Grade Clinical 9 Yes NAACCR #3843
gradeClinical
All SSDI
Grade Pathological 9 Yes NAACCR #3844
gradePathological
All SSDI
Grade Post Therapy Clin (yc) <BLANK> No NAACCR #1068
gradePostTherapyClin
COC
NPCR
SEER
SSDI
Grade Post Therapy Path (yp) <BLANK> No NAACCR #3845
gradePostTherapy
CCCR/Canada
COC
NPCR
SEER
SSDI
Brain Molecular Markers 88 No NAACCR #3816
brainMolecularMarkers
NPCR
SEER
SSDI
Chromosome 1p Status 8 No NAACCR #3801
chromosome1pLossHeterozygosity
COC
SEER
SSDI
Chromosome 19q Status 8 No NAACCR #3802
chromosome19qLossHeterozygosity
COC
SEER
SSDI
MGMT 8 No NAACCR #3889
methylationOfO6MGMT
COC
SEER
SSDI
Brain Primary Tumor Location <BLANK> No NAACCR #3964
brainPrimaryTumorLocation
CCCR/Canada 2024–
COC 2024–
NPCR 2024–
SEER 2024–
SSDI 2024–