Oropharynx HPV-Mediated (p16+)
Primary Site | Histology | Schema Discriminator 1 | Schema Discriminator 2 |
---|---|---|---|
C019, C024, C051-C052, C090-C091, C098-C099, C100, C102-C104, C108-C109 | 8000-8700 | 2 | |
C111 | 8000-8700 | 2 | 2 |
Notes
C019, C024, C051-C052, C090-C091, C098-C099, C100, C102-C104, C108-C109 and Schema Discriminator 2: Oropharyngeal p16: 2 (8000-8700) C111 and Schema Discriminator 1: Nasopharynx/PharyngealTonsil: 2 AND Schema Discriminator 2: Oropharyngeal p16: 2 (8000-8700) C019 Base of tongue, NOS C024 Lingual tonsil C051 Soft palate, NOS C052 Uvula C090 Tonsillar fossa C091 Tonsillar pillar C098 Overlapping lesion of tonsil C099 Tonsil, NOS C100 Vallecula C102 Lateral wall of oropharynx C103 Posterior wall of oropharynx C104 Branchial cleft (site of neoplasm) C108 Overlapping lesion of oropharynx C109 Oropharynx, NOS C111 Pharyngeal tonsil **Note 1:** The following sources were used in the development of this schema * SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998) (https://seer.cancer.gov/archive/manuals/EOD10Dig.3rd.pdf) * SEER Summary Staging Manual-2000: Codes and Coding Instructions (https://seer.cancer.gov/tools/ssm/ssm2000/) * Collaborative Stage Data Collection System, version 02.05: https://cancerstaging.org/cstage/Pages/default.aspx * Chapter 10 *HPV-Mediated (p16+) Oropharyngeal Cancer*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois. **Note 2:** See the following schemas for the listed histologies * C019, C024, C051-C052, C090-C091, C098-C099, C100, C102-C104, C108-C109 and Schema Discriminator 2: Oropharyngeal p16: 1, 9 (8000-8700): *Oropharynx (p16-)* * C111 and Schema Discriminator 1: Nasopharynx/PharyngealTonsil:1 (8000-8700): *Nasopharynx* * 8710-8714, 8800-8803, 8810-8905, 8912, 8921, 8932-8934, 8940-8990, 9000-9016, 9030-9043, 9045-9110, 9121-9138, 9141-9230, 9240-9580, 9582: *Soft Tissue Head and Neck* * 8720-8790: *Melanoma Head and Neck* * 8804-8806, 8910, 8920, 8930-8931, 8991, 9020, 9044, 9120, 9231, 9581: *Soft Tissue Rare* * 8935-8936: *GIST* * 8992: *Soft Tissue Other* * 9140: *Kaposi Sarcoma* * 9700-9701: *Mycosis Fungoides* **Note 3:** p16 immunotesting is mandatory to use this staging system for HPV-associated cancer. HPV by in situ hybridization (ISH) may be done as an alternative. If a case of oropharyngeal cancer has p16+, then this schema is used. If a case if p16- or does not have p16, then the Oropharynx (p16-) schema is used.Data Items
Name | Default Value | Used for Staging | NAACCR Item | Required By | Metadata |
---|---|---|---|---|---|
Year of Diagnosis | <BLANK> | No |
NAACCR #390
dateOfDiagnosis |
None | |
Primary Site | <BLANK> | Yes |
NAACCR #400
primarySite |
None | |
Histology | <BLANK> | Yes |
NAACCR #522
histologicTypeIcdO3 |
None | |
Behavior | <BLANK> | Yes |
NAACCR #523
behaviorCodeIcdO3 |
None | |
Schema Discriminator 1 | <BLANK> | Yes |
NAACCR #3926
schemaDiscriminator1 |
All | SSDI |
Schema Discriminator 2 | 9 | Yes |
NAACCR #3927
schemaDiscriminator2 |
All | SSDI |
Tumor Size Clinical | <BLANK> | No |
NAACCR #752
tumorSizeClinical |
None | |
Tumor Size Pathological | <BLANK> | No |
NAACCR #754
tumorSizePathologic |
None | |
Tumor Size Summary | 999 | Yes |
NAACCR #756
tumorSizeSummary |
None | |
Regional Nodes Positive | 99 | Yes |
NAACCR #820
regionalNodesPositive |
None | |
Regional Nodes Examined | 99 | No |
NAACCR #830
regionalNodesExamined |
None | |
LVI | 9 | No |
NAACCR #1182
lymphVascularInvasion |
None | |
RX Summ Surgery/Radiation Sequence | <BLANK> | No |
NAACCR #1380
rxSummSurgRadSeq |
None | |
RX Summ Systemic/Surgery Sequence | <BLANK> | No |
NAACCR #1639
rxSummSystemicSurSeq |
None | |
EOD Primary Tumor | 999 | Yes |
NAACCR #772
eodPrimaryTumor |
None | |
EOD Regional Nodes | 999 | Yes |
NAACCR #774
eodRegionalNodes |
None | |
EOD Mets | 00 | Yes |
NAACCR #776
eodMets |
None | |
SS2018 | <BLANK> | No |
NAACCR #764
summaryStage2018 |
None | |
Grade Clinical | 9 | No |
NAACCR #3843
gradeClinical |
CCCR/Canada COC NPCR SEER |
SSDI |
Grade Pathological | 9 | No |
NAACCR #3844
gradePathological |
CCCR/Canada COC NPCR SEER |
SSDI |
Grade Post Therapy Clin (yc) | <BLANK> | No |
NAACCR #1068
gradePostTherapyClin |
COC NPCR SEER |
SSDI |
Grade Post Therapy Path (yp) | <BLANK> | No |
NAACCR #3845
gradePostTherapy |
CCCR/Canada COC NPCR SEER |
SSDI |
Extranodal Exten H&N Clin | 8 | No |
NAACCR #3831
extranodalExtensionHeadNeckClin |
COC SEER (RC) |
SSDI |
Extranodal Exten H&N Path | X.8 | No |
NAACCR #3832
extranodalExtensionHeadNeckPath |
CCCR/Canada COC SEER |
SSDI |
Lymph Nodes Size of Mets | XX.8 | Yes |
NAACCR #3883
lnSize |
All | SSDI |
SEER_SSF1: SEER Site-Specific Fact 1 | 9 | No |
NAACCR #3700
seerSiteSpecificFact1 |
None |
Initial Context
Outputs
Name | Default Value | Description | NAACCR Item | Metadata |
---|---|---|---|---|
Schema ID | 00100 |
NAACCR #3800
schemaId |
None | |
Derived Version | {{ctx_alg_version}} | None | None | |
Derived Summary Stage 2018 | 9 |
NAACCR #762
derivedSummaryStage2018 |
None |