Grade Clinical

This input is used in derivation

Notes

**Note 1:** Grade Clinical must not be blank. **Note 2:** Assign the highest grade from the primary tumor assessed during the clinical time frame. **Note 3:** If there are multiple tumors with different grades abstracted as one primary, code the highest grade. **Note 4:** Codes 1-3 take priority over codes A-D. * Grades A-D should only be used in the absence of a physician's statement of grade (G1, G2, G3) or no results for Ki-67 or Mitotic Count (See also Note 6) **Note 5:** Do not code grade based on the following terminology: * Neuroendocrine carcinoma, low grade (8240/3) * Neuroendocrine carcinoma, well differentiated (8240/3) * Neuroendocrine carcinoma, moderately differentiated (8249/3) * Poorly differentiated neuroendocrine carcinoma (8246/3) **Note 6:** Code grade based on the physician's documentation (G1, G2, G3) OR **in the absence of a physician's statement,** code grade based on the Ki-67 and Mitotic Count. * If a Ki-67 is documented as less than 3, many times the mitotic count is not done. In this situation, the Ki-67 alone is enough to code the grade (G1). * Grades 2 and 3, are either/or for Ki-67 and Mitotic Count. You do not need both the Ki-67 and Mitotic Count to assign grade 2 or 3. **Note 7:** Code 9 (unknown) when * Grade from primary site is not documented * Clinical workup is not done (for example, cancer is an incidental finding during surgery for another condition) * Grade checked "not applicable" on CAP Protocol (if available) and no other grade information is available **Note 8:** If there is only one grade available and it cannot be determined if it is clinical or pathological, assume it is a Grade Clinical and code appropriately per Grade Clinical categories for that site, and then code unknown (9) for Grade Pathological, and blank for Grade Post Therapy Clin (yc) and Grade Post Therapy Path (yp).

Default

9

NAACCR Item

NAACCR #3843

Metadata

SSDI
Code Description
1 G1: Mitotic count (per 2mm2) less than 2 AND Ki-67 index (%) less than 3 Stated as WHO Grade 1
2 G2: Mitotic count (per 2mm2) equal 2-20 OR Ki-67 index (%) equal 3-20 Stated as WHO Grade 2
3 G3: Mitotic count (per 2mm2) greater than 20 OR Ki-67 index (%) greater than 20 Stated as WHO Grade 3
A Well differentiated
B Moderately differentiated
C Poorly differentiated
D Undifferentiated, anaplastic
9 Grade cannot be assessed (GX); Unknown