AFP (Alpha Fetoprotein) Post-Orchiectomy Range
Description
AFP (Alpha Fetoprotein) Post-Orchiectomy Range identifies the range category of the lowest AFP value measured post-orchiectomy. AFP is a serum tumor marker that is often elevated in patients with nonseminomatous germ cell tumors of the testis. The Post-Orchiectomy lab value is used to monitor response to therapy.
For Testis, there are 4 related data items that record information on AFP for Testis.
* 3805: AFP Post-Orchiectomy Lab Value
* 3806: AFP Post-Orchiectomy Range
* 3807: AFP Pre-Orchiectomy Lab Value
* 3808: AFP Pre-Orchiectomy Range
Rationale
AFP (Alpha Fetoprotein) Post-Orchiectomy Range is a Registry Data Collection Variable in AJCC. AFP (Alpha Fetoprotein) Post-Orchiectomy Range is used to assign the S Category Pathological and was previously collected as Testis CS SSF #13.
Additional Info
**Source documents:** clinical laboratory report (blood serum radioimmunoassay or enzyme assay (EIA)); sometimes in history and physical or clinical statement in pathology report
**Other names include** AFP, aFP, Alpha Fetoprotein, Alpha-fetoprotein, alpha-fetoprotein, fetal alpha globulin
For further information, refer to the **Testis** cancer protocol published by the College of American Pathologists for the AJCC Staging System *Testis*
**Normal Reference Range**
* Adult men 0-15 ng/ml (SI: 0-15 µg/L)**
**Measurements**
* A lab value expressed in micrograms/liter (ug/L) is equivalent to the same value expressed in nanograms/milliliter (ng/mL).
* ***Example***: 10 IU/mL: 10/0.83 = 12.04 ng/mL; 5 IU/mL: 5/0.83= 6.02 ng/mL
* If the lab value is expressed in IU/ml, use the following conversion: 1 ng/mL = 0.83 IU/mL
* To calculate ng from IU/mL, divide the value for IU by 0.83.
* ***Example***: 10 IU/mL: 10/0.83 = 12.04 ng/mL; 5 IU/mL: 5/0.83= 6.02 ng/mL
Notes
**Note 1:** **Physician Statement**
* Physician statement of the AFP (Alpha Fetoprotein) Post-Orchiectomy Range can be used to code this data item when there is no other information available.
**Note 2:** **Timing**
* Record the range of the AFP test as documented in the medical record **after orchiectomy** but prior to adjuvant therapy. The lab value may be documented in a lab report, history and physical, or clinical statement in the pathology report.
**Note 3:** **Lab values elevated after orchiectomy**
* If the initial post-orchiectomy AFP remains elevated, review subsequent tests and record the lowest AFP value (normalization or plateau) prior to adjuvant therapy or before the value rises again.
**Note 4:** **Pre-orchiectomy AFP normal**
* If the pre-orchiectomy AFP was normal, a post-orchiectomy AFP may not be performed. In this case, code 5 should be recorded.
**Note 5:** **Related data item**
* The same laboratory test should be used to record the related data item 3805: AFP Post-Orchiectomy Lab Value.
Default
8
Metadata
SSDI
| Code |
Description |
| 0 |
Within normal limits |
| 1 |
Above normal and less than 1,000 nanograms/milliliter (ng/mL) |
| 2 |
1,000 -10,000 ng/mL |
| 3 |
Greater than 10,000 ng/mL |
| 4 |
Post-Orchiectomy alpha fetoprotein (AFP) stated to be elevated |
| 5 |
Post-Orchiectomy alpha fetoprotein (AFP) unknown or not done but pre-orchiectomy AFP was normal |
| 7 |
Test ordered, results not in chart |
| 8 |
Not applicable: Information not collected for this case
(If this information is required by your standard setter, use of code 8 may result in an edit error.) |
| 9 |
Not documented in medical record
No orchiectomy performed
AFP (Alpha Fetoprotein) Post-Orchiectomy Range not assessed or unknown if assessed |
