Mitotic Count Uveal Melanoma
Description
Mitotic Count Uveal Melanoma, the number of mitoses per 40 high-power fields (HPF) based on pathological evaluation, is a prognostic factor for uveal melanoma.
Mitotic count is collected for several different types of cancers. For melanomas of the choroids, ciliary body and iris, the standard measurement is the total number of mitoses per 40 high power fields (HPF at 40 times magnification) per 0.152 square millimeters.
Rationale
Mitotic Count Uveal Melanoma is listed as a Registry Data Collection Variable in AJCC. It was previously collected as Uveal Melanoma, CS SSF #9.
Additional Info
**Source documents:** pathology report
For further information, refer to the **Uveal Melanoma** cancer protocol published by the College of American Pathologists for the AJCC Staging System *Uveal Melanoma*
Notes
**Note 1:** **Physician Statement**
* Physician statement of mitotic count for a uveal melanoma can be used to code this data item when no other information is available.
**Note 2:** **Mitotic count defined**
* The number of mitoses per 40 high-power fields (HPF), reflects the potential aggressiveness or prognosis of uveal melanomas
* This data item presumes the denominator of 40 HPF, so just the numerator (the mitotic count) is coded here.
* For other schemas in which mitotic count is collected, the denominator may vary.
**Note 3:** **High Power Field (HPF) defined**
* An HPF usually has a magnification objective of 40 (a 40x field)
* As described in the AJCC chapter on Uveal Melanomas, the typical field area is 0.152 square millimeters (mm2).
**Note 4:** **Recording the results**
* Record mitotic count to the nearest tenth as documented in the pathology report.
* For example, a mitotic count of 6/40 HPF would be coded 6.0.
Default
XX.8
Metadata
SSDI
| Code |
Description |
| 0.0 |
0 mitoses per 40 high-power fields (HPF)
Mitoses absent, no mitoses present, no mitotic activity |
| 0.1-99.9 |
0.1-99.9 mitosis per 40 HPF |
| XX.1 |
100 or more mitoses per 40 HPF |
| XX.2 |
Stated as low mitotic count or rate with no specific number |
| XX.3 |
Stated as high mitotic count or rate with no specific number |
| XX.4 |
Mitotic count described with denominator other than 40 HPF |
| XX.7 |
Test ordered, results not in chart |
| XX.8 |
Not applicable: Information not collected for this case
(If this information is required by your standard setter, use of code XX.8 may result in an edit error.) |
| XX.9 |
Not documented in medical record
Mitotic Count Uveal Melanoma not assessed or unknown if assessed |
