Multigene Signature Result
Description
Multigene signatures or classifiers are assays of a panel of genes from a tumor specimen, intended to provide a quantitative assessment of the likelihood of response to chemotherapy and to evaluate prognosis or the likelihood of future metastasis. This data item identifies the multigene signature result. Oncotype Dx is coded elsewhere.
Rationale
Multigene Signature Results is a Registry Data Collection Variable in AJCC. It was previously collected as Breast, CS SSF #23. See also Multigene Signature Method.
Additional Info
**Source documents:** specialty reference laboratories (private companies with proprietary testing methods); the actual report may be included in the medical record or may be referenced by the clinician.
**Other names include:** genomic profiling, multigene testing, multigene assay, microarray assay, molecular diagnostics for treatment planning
Notes
**Note 1:** **Physician Statement**
* Physician statement of the Multigene Signature Results can be used to code this data item when no other information is available.
**Note 2:** **Score or Risk**
* Code the score or risk for the test performed. The same test should be used to record the related data item 3894: Multigene Signature Method.
**Note 3:** **Oncotype Dx tests**
* Oncotype Dx tests are not recorded in this data item. See the following related data items for Oncotype Dx.
* 3903: Oncotype Dx Recurrence Score-DCIS
* 3904: Oncotype Dx Recurrence Score-Invasive
* 3905: Oncotype Dx Risk Level-DCIS
* 3906: Oncotype Dx Risk Level-Invasive
Default
X8
Metadata
SSDI
| Code |
Description |
| 00-99 |
Enter actual recurrence score
Note: Depending on the test, the range of values may be different |
| X1 |
Score 100 |
| X2 |
Low risk |
| X3 |
Moderate [intermediate] risk |
| X4 |
High risk |
| X7 |
Test done, results not in chart |
| X8 |
Not applicable: Information not collected for this case
(If this item is required by your standard setter, use of code X8 will result in an edit error.) |
| X9 |
Not documented in medical record
Multigene Signature Results not assessed or unknown if assessed |
