Summary Stage 2018: Brain

Summary Stage 2018

Notes

**Brain** **Any behavior:** * 8000-8700, 8720-8790, 8802, 8810, 8815, 8850, 8890, 8900, 9064, 9070-9071, 9080, 9084-9085, 9100-9105, 9120, 9133, 9140, 9180, 9220, 9364, 9380-9460, 9480-9500, 9505-9507, 9509-9540, 9680, 9699, 9702-9715, 9751-9759 * 8710-8714, 8800-8801, 8803, 8811-8814, 8816-8818, 8820-8842, 8851-8858, 8860-8881, 8891-8898, 8902-8905, 8921, 8932-8934, 8940-8990, 8992, 9000-9016, 9030-9043, 9045-9063, 9065, 9072-9073, 9081-9083, 9086-9091, 9110-9111, 9121-9132, 9135-9138, 9141-9175, 9181-9213, 9221, 9230, 9240-9361, 9363, 9365, 9370-9373, 9541-9580, 9582 (2023+) * For years 2018-2022, see *Soft Tissue* * 9671 (2023+) * For years 2018-2022, see *Myeloma and Plasma Cell Disorders* * 9690, 9719 (2023+) * For years 2018-2022, see *Lymphoma* * 9362, 9470-9478, 9501-9504, 9508 (2018-2022 only) * For 2023+, see *Medulloblastoma* **Benign/Borderline histologies (/0, /1):** * 8804-8806, 8859, 8901, 8910-8920, 8930-8931, 8935-8936, 8991, 9020, 9044, 9222, 9231, 9366-9368, 9581, 9590-9663, 9673-9679, 9687-9689, 9691-9698, 9700-9701, 9716-9718, 9724-9742, 9761-9765, 9767-9993 C700, C710-C719 C700 Cerebral meninges C710 Cerebrum C711 Frontal lobe C712 Temporal lobe C713 Parietal lobe C714 Occipital lobe C715 Ventricle, NOS C716 Cerebellum, NOS C717 Brain stem C718 Overlapping lesion of brain C719 Brain, NOS **Note 1:** **Sources used in the development of this chapter** * SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998) (https://seer.cancer.gov/archive/manuals/EOD10Dig.3rd.pdf) * SEER Summary Staging Manual-2000: Codes and Coding Instructions (https://seer.cancer.gov/tools/ssm/ssm2000/) * Collaborative Stage Data Collection System, version 02.05: https://cancerstaging.org/cstage/Pages/default.aspx * Chapter 72 *Brain and Spinal Cord*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois. * Brain and Spinal Cord, from the AJCC Cancer Staging System Version 9 (2022). Used with permission of the American College of Surgeons, Chicago, Illinois. **Note 2:** **Medulloblastoma** * For diagnoses January 1, 2023, and forward, the following histologies will be collected in the Medulloblastoma Summary Stage chapter * 9362, 9470-9478, 9501-9504, 9508 * *Exception:* For C723 and 9473/3, see Orbital Sarcoma **Note 3:** **Other Summary Stage Chapters with Brain sites (/3 only)** * **GIST**: 8935-8936 * **Lymphoma**: 9590, 9596-9663, 9673-9679, 9687-9698, 9716-9719, 9725-9726, 9735, 9737-9738, 9826-9827 * *Note:* 9690, 9719 for 2018-2022 only * **Mycosis Fungoides**: 9700-9701 * **Plasma cell disorders**: 9671, 9731, 9734, 9761 * *Note:* 9671 for 2018-2022 only * **Soft Tissue**: 8804-8806, 8859, 8901, 8910-8920, 8930-8931, 8991, 9020, 9044, 9222, 9231, 9366-9368, 9581 **Note 4:** **Only staging system** * Summary Stage is the only applicable staging system for this site/histology/schema. **Note 5:** **Benign/Borderline tumors** * Benign (/0) or Borderline (/1) tumors **are always coded to 8** regardless of size, extension to adjacent sites, or multiple tumors **Note 6:** **Not applicable codes** * Codes 0, 3, and 4 are not applicable for this chapter. **Note 7:** **Infratentorial and Supratentorial** * The tentorium cerebelli is an extension of the dura mater that separates the cerebellum from the inferior portion of the occipital lobes. * The location of the tumor above or below the tentorium can help in determining the type of tumor; also, most adult brain tumors are supratentorial, and most pediatric brain tumors are infratentorial. * In the following list, note that ICD-O-3 codes C710 and C719 include both supratentorial and infratentorial subsites. - The following subsites are **Infratentorial** * All subsites for codes C716-C717 * Hypothalamus (C710) * Pallium (C710) * Posterior cranial fossa (C719) * Thalamus (C710) - The following subsites are **Supratentorial** * All subsites for codes C711-C715 * Primary site C710 (excluding hypothalamus, pallium, thalamus) * Anterior cranial fossa (C719) * Corpus callosum (C718) * Middle cranial fossa (C719) * Tapetum (C718) * Suprasellar (C719) **Note 8:** **Midline shift** * A midline shift is not the same thing as crossing the midline (code 2). * Documentation must state “crossing/crosses the midline”

NAACCR Item

NAACCR #764

Metadata

None
SS2018 Description
1 **Localized only (localized, NOS)** - Confined to brain, NOS - Confined to meninges, NOS - Confined to ventricles + Tumor invades or encroaches upon ventricular system - Infratentorial tumor confined to + Brain stem or meninges of brain stem (one side) * Medulla oblongata * Midbrain (mesencephalon) * Pons + Cerebellum or meninges of cerebellum (one side or midline) * Lateral lobes * Median lobe of cerebellum * Vermis + Hypothalamus + Thalamus - Infratentorial tumor + Both cerebellum and brain stem involved with tumor on one side - Supratentorial tumor confined to + Cerebral hemisphere (cerebrum) or meninges of cerebral hemisphere (one side) * Frontal lobe * Occipital lobe * Parietal lobe * Temporal lobe
2 **Regional by direct extension only** Tumor crosses the midline * All sites - Bone (skull) - Contralateral hemisphere - Corpus callosum (including splenium) - Major blood vessel(s) - Meninges (e.g., dura) - Nerves (cranial, NOS) - Spinal cord/canal - Supratentorial tumor extends/invades infratentorially to involve + Brain stem + Cerebellum + Hypothalamus + Pallium + Posterior cranial fossa + Thalamus - Infratentorial tumor extends/invades supratentorially to involve + Anterior cranial fossa + Cerebrum (cerebral hemisphere) (excluding hypothalamus, pallium, thalamus) + Corpus callosum + Middle cranial fossa + Suprasellar brain + Tapetum
7 **Distant site(s)/lymph node(s) involved** - Distant site(s) (including further contiguous extension) + Circulating cells in cerebral spinal fluid (CSF) + Nasal cavity + Nasopharynx + Other direct extension outside CNS + Posterior pharynx - Distant lymph node(s), NOS - Distant metastasis, NOS + Carcinomatosis + Distant metastasis WITH or WITHOUT distant lymph node(s) + Metastasis within CNS and CSF pathways * "Drop" metastasis * Extra-neural metastasis * Metastasis outside the CNS
8 **Benign or borderline brain** * Behavior is /0 or /1
9 Unknown if extension or metastasis
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998 (2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001. (3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05.** American Joint Committee on Cancer (Chicago, IL) (4) Laws, E.R., Curran, W.J., et al. **Brain and Spinal Cord**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017 (5) **Brain and Spinal Cord**, from the AJCC Cancer Staging System Version 9 (2022). Used with permission of the American College of Surgeons, Chicago, Illinois.