Summary Stage 2018: Brain
Summary Stage 2018
Notes
**Brain**
**Any behavior:**
* 8000-8700, 8720-8790, 8802, 8810, 8815, 8850, 8890, 8900, 9064, 9070-9071, 9080, 9084-9085, 9100-9105, 9120, 9133, 9140, 9180, 9220, 9364, 9380-9460, 9480-9500, 9505-9507, 9509-9540, 9680, 9699, 9702-9715, 9751-9759
* 8710-8714, 8800-8801, 8803, 8811-8814, 8816-8818, 8820-8842, 8851-8858, 8860-8881, 8891-8898, 8902-8905, 8921, 8932-8934, 8940-8990, 8992, 9000-9016, 9030-9043, 9045-9063, 9065, 9072-9073, 9081-9083, 9086-9091, 9110-9111, 9121-9132, 9135-9138, 9141-9175, 9181-9213, 9221, 9230, 9240-9361, 9363, 9365, 9370-9373, 9541-9580, 9582 (2023+)
* For years 2018-2022, see *Soft Tissue*
* 9671 (2023+)
* For years 2018-2022, see *Myeloma and Plasma Cell Disorders*
* 9690, 9719 (2023+)
* For years 2018-2022, see *Lymphoma*
* 9362, 9470-9478, 9501-9504, 9508 (2018-2022 only)
* For 2023+, see *Medulloblastoma*
**Benign/Borderline histologies (/0, /1):**
* 8804-8806, 8859, 8901, 8910-8920, 8930-8931, 8935-8936, 8991, 9020, 9044, 9222, 9231, 9366-9368, 9581, 9590-9663, 9673-9679, 9687-9689, 9691-9698, 9700-9701, 9716-9718, 9724-9742, 9761-9765, 9767-9993
C700, C710-C719
C700 Cerebral meninges
C710 Cerebrum
C711 Frontal lobe
C712 Temporal lobe
C713 Parietal lobe
C714 Occipital lobe
C715 Ventricle, NOS
C716 Cerebellum, NOS
C717 Brain stem
C718 Overlapping lesion of brain
C719 Brain, NOS
**Note 1:** The following sources were used in the development of this chapter
* SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998) (https://seer.cancer.gov/archive/manuals/EOD10Dig.3rd.pdf)
* SEER Summary Staging Manual-2000: Codes and Coding Instructions (https://seer.cancer.gov/tools/ssm/ssm2000/)
* Collaborative Stage Data Collection System, version 02.05: https://cancerstaging.org/cstage/Pages/default.aspx
* Chapter 72 *Brain and Spinal Cord*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois.
* Brain and Spinal Cord, from the AJCC Cancer Staging System Version 9 (2022). Used with permission of the American College of Surgeons, Chicago, Illinois.
**Note 2:** For diagnoses January 1, 2023 and forward, see the following Summary Stage chapter for the listed histologies (any behavior)
* 9362, 9470-9478, 9501-9504, 9508: *Medulloblastoma*
**Note 3:** See the following chapters for the listed /3 histologies
* 8804-8806, 8859, 8901, 8910-8920, 8930-8931, 8991, 9020, 9044, 9222, 9231, 9366-9368, 9581: *Soft Tissue*
* 9590, 9596-9663, 9673-9679, 9687-9698, 9716-9719, 9725-9726, 9735, 9737-9738, 9826-9827: *Lymphoma*
* *Note:* 9690, 9719 for 2018-2022 only
* 8935-8936: *GIST*
* 9700-9701: *Mycosis Fungoides*
* 9671, 9731, 9734, 9761: *Plasma Cell Disorders*
* *Note:* 9671 for 2018-2022 only
**Note 4:** Summary Stage is the only applicable staging system for this site/histology/schema.
**Note 5:** Assign code 8 for benign or borderline tumors.
**Note 6:** Codes 0, 3, and 4 are not applicable for this chapter.
**Note 7:** The tentorium cerebelli is an extension of the dura mater that separates the cerebellum from the inferior portion of the occipital lobes. The location of the tumor above or below the tentorium can help in determining the type of tumor; also most adult brain tumors are supratentorial, and most pediatric brain tumors are infratentorial. In the following list, note that ICD-O-3 codes C710 and C719 include both supratentorial and infratentorial subsites.
- The following subsites are **Infratentorial**
* All subsites for codes C716-C717
* Hypothalamus (C710)
* Pallium (C710)
* Posterior cranial fossa (C719)
* Thalamus (C710)
- The following subsites are **Supratentorial**
* All subsites for codes C711-C715
* Primary site C710 (excluding hypothalamus, pallium, thalamus)
* Anterior cranial fossa (C719)
* Corpus callosum (C718)
* Middle cranial fossa (C719)
* Tapetum (C718)
* Suprasellar (C719)
**Note 8:** A midline shift is not the same thing as crossing the midline (code 2)
* It must state tumor **crosses the midline**
Metadata
None
| SS2018 |
Description |
| 1 |
Localized only (localized, NOS)
- Confined to brain, NOS
- Confined to meninges, NOS
- Confined to ventricles
+ Tumor invades or encroaches upon ventricular system
- Infratentorial tumor confined to
+ Brain stem or meninges of brain stem (one side)
* Medulla oblongata
* Midbrain (mesencephalon)
* Pons
+ Cerebellum or meninges of cerebellum (one side or midline)
* Lateral lobes
* Median lobe of cerebellum
* Vermis
+ Hypothalamus
+ Thalamus
- Infratentorial tumor
+ Both cerebellum and brain stem involved with tumor on one side
- Supratentorial tumor confined to
+ Cerebral hemisphere (cerebrum) or meninges of cerebral hemisphere (one side)
* Frontal lobe
* Occipital lobe
* Parietal lobe
* Temporal lobe |
| 2 |
Regional by direct extension only
- Bone (skull)
- Contralateral hemisphere
- Corpus callosum (including splenium)
- Major blood vessel(s)
- Meninges (e.g., dura)
- Nerves (cranial, NOS)
- Spinal cord/canal
- Supratentorial tumor extends infratentorially to involve
+ Brain stem
+ Cerebellum
+ Hypothalamus
+ Pallium
+ Posterior cranial fossa
+ Thalamus
- Infratentorial tumor extends supratentorially to involve
+ Anterior cranial fossa
+ Cerebrum (cerebral hemisphere) (excluding hypothalamus, pallium, thalamus)
+ Corpus callosum
+ Middle cranial fossa
+ Suprasellar brain
+ Tapetum
- Tumor crosses the midline |
| 7 |
Distant site(s)/lymph node(s) involved
- Distant site(s) (including further contiguous extension)
+ Circulating cells in cerebral spinal fluid (CSF)
+ Nasal cavity
+ Nasopharynx
+ Other direct extension outside CNS
+ Posterior pharynx
- Distant lymph node(s), NOS
- Distant metastasis, NOS
+ Carcinomatosis
+ Distant metastasis WITH or WITHOUT distant lymph node(s)
+ Metastasis within CNS and CSF pathways
* "Drop" metastasis
* Extra-neural metastasis
* Metastasis outside the CNS |
| 8 |
Benign or borderline brain |
| 9 |
Unknown if extension or metastasis |
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998
(2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001.
(3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05.** American Joint Committee on Cancer (Chicago, IL)
(4) Laws, E.R., Curran, W.J., et al. **Brain and Spinal Cord**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017
(5) **Brain and Spinal Cord**, from the AJCC Cancer Staging System Version 9 (2022). Used with permission of the American College of Surgeons, Chicago, Illinois.
