Grade Post Therapy Clin (yc)
Notes
**Note 1:** Leave Grade Post Therapy Clin (yc) blank when
* No neoadjuvant therapy
* Clinical or pathological case only
* Neoadjuvant therapy completed, no microscopic exam is done prior to surgery/resection of primary tumor
* There is only one grade available and it cannot be determined if it is clinical, pathological, post therapy clinical or post therapy pathological
**Note 2:** Assign the highest grade from the microscopically sampled specimen of the primary site following neoadjuvant therapy or primary systemic/radiation therapy.
**Note 3:** If there are multiple tumors with different grades abstracted as one primary, code the highest grade.
**Note 4:** Codes 1-4 take priority over codes A-D.
**Note 5:** Code 9 (unknown) when
* Microscopic exam is done after neoadjuvant therapy and grade from the primary site is not documented
* Microscopic exam is done after neoadjuvant therapy and there is no residual cancer
* Grade checked “not applicable” on CAP Protocol (if available) and no other grade information is available
Metadata
SSDI
| Code |
Description |
| 1 |
G1: Nucleoli absent or inconspicuous and basophilic at 400x magnification
Stated as WHO/ISUP Grade 1 |
| 2 |
G2: Nucleoli conspicuous and eosinophilic at 400x magnification, visible but not prominent at 100x magnification
Stated as WHO/ISUP Grade 2 |
| 3 |
G3: Nucleoli conspicuous and eosinophilic at 100x magnification
Stated as WHO/ISUP Grade 3 |
| 4 |
G4: Marked nuclear pleomorphism and/or multinucleate giant cells and/or rhabdoid and/or sarcomatoid differentiation
Stated as WHO/ISUP Grade 4 |
| A |
Well differentiated |
| B |
Moderately differentiated |
| C |
Poorly differentiated |
| D |
Undifferentiated, anaplastic |
| 9 |
Grade cannot be assessed (GX); Unknown
Only Fuhrman grade documented |
| <BLANK> |
See Note 1 |
