Summary Stage 2018: Corpus Carcinoma and Carcinosarcoma

Summary Stage 2018

Notes

**Corpus Carcinoma and Carcinosarcoma** 8000-8700, 8720-8790, 8950, 8980 C540-C543, C548-C549, C559 C540 Isthmus uteri C541 Endometrium C542 Myometrium C543 Fundus uteri C548 Overlapping lesion of corpus uteri C549 Corpus uteri C559 Uterus, NOS **Note 1:** The following sources were used in the development of this chapter * SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998) (https://seer.cancer.gov/archive/manuals/EOD10Dig.3rd.pdf) * SEER Summary Staging Manual-2000: Codes and Coding Instructions (https://seer.cancer.gov/tools/ssm/ssm2000/) * Collaborative Stage Data Collection System, version 02.05: https://cancerstaging.org/cstage/Pages/default.aspx * Chapter 53 *Corpus Uteri-Carcinoma and Carcinosarcoma*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois. **Note 2:** See the following schemas for the listed histologies * 8710-8714, 8800-8941, 8951-8976, 8981-9110, 9120-9138, 9141-9582: *Corpus Sarcoma* * 9140: *Kaposi Sarcoma* * 9700-9701: *Mycosis Fungoides* **Note 3:** Isolated tumor cells (ITCs) are defined as single tumor cells or small clusters not greater than 0.2 mm, usually detected by immunohistochemical (IHC) or molecular methods. ITCs do not usually show evidence of malignant activity (e.g., proliferation or stromal reaction). * Lymph nodes with ITCs only are **not** counted as positive nodes for Summary Stage

NAACCR Item

NAACCR #764
SS2018 Description
0 In situ, intraepithelial, noninvasive, preinvasive Endometrial intraepithelial carcinoma (EIC) (8380/2) Serous endometrial intraepithelial carcinoma (SEIC) (8441/2)
1 Localized only (localized, NOS) * Confined to endometrium (glandular or stromal) * Invasion of myometrium (inner half, outer half, NOS) + WITHOUT or UNKNOWN involvement of endocervix Confined to corpus, NOS Localized, NOS FIGO Stage I (IA, IB, I NOS)
2 Regional by direct extension only * Adnexa (direct extension or metastasis) * Bladder wall * Bladder, NOS excluding mucosa (see code 7 for mucosa) * Cervix (glandular or stromal) * Cervix uteri, NOS, but not beyond uterus * Endocervix (glandular or stromal) * Extension beyond uterus, within pelvis, NOS * Fallopian tube(s) * "Frozen pelvis" (clinically described) * Ligament(s) (broad, ovarian, round, suspensory) * Myometrium WITH involvement of endocervix * Ovary(ies) * Parametrium * Parietal serosa of pelvic wall * Pelvic wall(s) * Rectal wall * Rectum, NOS excluding mucosa (see code 7 for mucosa) * Serosa * Tunica serosa (visceral peritoneum of corpus, serosa covering the corpus) * Ureter * Vagina * Visceral peritoneum of pelvic organs excluding serosa of corpus * Vulva Malignant cells in peritoneal cytology FIGO Stage II FIGO Stage III (IIIA, IIIB, III NOS)
3 Regional lymph node(s) involved only - Para-aortic, NOS + Aortic + Lateral aortic/lateral lumbar + Periaortic - Pelvic, NOS + Iliac, NOS + Common + External + Internal (hypogastric) (obturator) + Paracervical + Parametrial + Sacral, NOS + Lateral (laterosacral) + Middle (promontorial) (Gerota's node) + Presacral + Uterosacral - Regional lymph node(s), NOS + Lymph node(s), NOS FIGO Stage IIIC (IIIC1, IIIC2, IIIC NOS) * Localized tumor WITH regional lymph node involvement
4 Regional by BOTH direct extension AND regional lymph node(s) involved - Codes (2) + (3)
7 Distant site(s)/lymph node(s) involved - Distant site(s) (including further contiguous extension) + Abdominal serosa (visceral or parietal peritoneum of abdomen) + Abdominal structures (other, NOS) + Abdominal tissue (infiltration) + Bladder mucosa (excluding bullous edema) + Bone + Bowel mucosa + Cul de sac (rectouterine pouch or Pouch of Douglas) + Intraperitoneal disease + Liver + Lung + Rectum mucosa (excluding bullous edema) + Sigmoid colon + Small intestine - Distant lymph node(s), NOS + Femoral + Inguinal, NOS + Inguinofemoral (groin) + Node of Cloquet or Rosenmuller (highest deep inguinal) + Superficial inguinal (femoral) - Distant metastasis, NOS + Carcinomatosis + Distant metastasis WITH or WITHOUT distant lymph node(s) FIGO Stage IV (IVA, IVB, IV NOS)
9 Unknown if extension or metastasis
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998 (2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001. (3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05.** American Joint Committee on Cancer (Chicago, IL) (4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging.** In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017 (5) **Introduction to Female Reproductive Organs**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017 (6) Powell, M.A., Olawaiye, A.B., Mutch, D.G., et al. **Corpus Uteri - Carcinoma and Carcinosarcoma**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017