Multigene Signature Result
Notes
**Note 1:** Physician statement of the Multigene Signature Results can be used to code this data item. **Note 2:** Multigene signatures or classifiers are assays of a panel of genes from a tumor specimen, intended to provide a quantitative assessment of the likelihood of response to chemotherapy and to evaluate prognosis or the likelihood of future metastasis. * Only record tests done on tumor tissue that help determine if the cancer is likely to recur. Don’t include other tests, such as those that evaluate hereditary mutations that influence a patient’s risk of developing cancer (e.g. myRisk, BRCA) **Note 3:** Code the score or risk for the test performed. The same test should be used to record information in Multigene Signature Method [NAACCR Data Item #3894]. **Note 4:** Oncotype Dx tests are not recorded in this data item. See the following data items for Oncotype Dx. * Oncotype Dx Recurrence Score-DCIS [NAACCR Data Item #3903] * Oncotype Dx Recurrence Score-Invasive [NAACCR Data Item #3904] * Oncotype Dx Risk Level-DCIS [NAACCR Data Item #3905] * Oncotype Dx Risk Level-Invasive [NAACCR Data Item #3906] **Note 5:** PAM50 (Prosigna) is a single numeric score of 0-100. If the score is available, record the score. If only the risk level is available, record that. **Note 6:** For Mammaprint, EndoPredict, and Breast Cancer Index, only record the risk level.Default
X8NAACCR Item
NAACCR #3895Metadata
SSDI| Code | Description |
|---|---|
| 00-99 | Enter actual recurrence score Note: Depending on the test, the range of values may be different |
| X1 | Score 100 |
| X2 | Low risk |
| X3 | Moderate [intermediate] risk |
| X4 | High risk |
| X7 | Test done, results not in chart |
| X8 | Not applicable: Information not collected for this case (If this item is required by your standard setter, use of code X8 will result in an edit error.) |
| X9 | Not documented in medical record Multigene Signature Results not assessed or unknown if assessed |