Multigene Signature Method
Notes
**Note 1:** Physician statement of the Multigene Signature Method can be used to code this data item.
**Note 2:** Multigene signatures or classifiers are assays of a panel of genes from a tumor specimen, intended to provide a quantitative assessment of the likelihood of response to chemotherapy and to evaluate prognosis or the likelihood of future metastasis.
* Only record tests done on tumor tissue that help determine if the cancer is likely to recur. Don’t include other tests, such as those that evaluate hereditary mutations that influence a patient’s risk of developing cancer (e.g. myRisk, BRCA)
**Note 3:** Code the type of test performed. The same test should be used to record information in Multigene Signature Results [NAACCR Data Item #3895].
**Note 4:** Oncotype Dx tests are not recorded in this data item. See the following data items for Oncotype Dx.
* Oncotype Dx Recurrence Score-DCIS [NAACCR Data Item #3903]
* Oncotype Dx Recurrence Score-Invasive [NAACCR Data Item #3904]
* Oncotype Dx Risk Level-DCIS [NAACCR Data Item #3905]
* Oncotype Dx Risk Level-Invasive [NAACCR Data Item #3906]
Default
8
Metadata
SSDI
| Code |
Description |
| 1 |
Mammaprint |
| 2 |
PAM50 (Prosigna) |
| 3 |
Breast Cancer Index |
| 4 |
EndoPredict |
| 5 |
Test performed, type of test unknown |
| 6 |
Multiple tests, any tests in codes 1-4 |
| 7 |
Test ordered, results not in chart |
| 8 |
Not applicable: Information not collected for this case
(If this item is required by your standard setter, use of code 8 will result in an edit error.) |
| 9 |
Not documented in medical record
Multigene Signature Method not assessed or unknown if assessed |
