Multigene Signature Method
Notes
**Note 1:** Physician statement of the Multigene Signature Method can be used to code this data item. **Note 2:** Multigene signatures or classifiers are assays of a panel of genes from a tumor specimen, intended to provide a quantitative assessment of the likelihood of response to chemotherapy and to evaluate prognosis or the likelihood of future metastasis. * Only record tests done on tumor tissue that help determine if the cancer is likely to recur. Don’t include other tests, such as those that evaluate hereditary mutations that influence a patient’s risk of developing cancer (e.g. myRisk, BRCA) **Note 3:** Code the type of test performed. The same test should be used to record information in Multigene Signature Results [NAACCR Data Item #3895]. **Note 4:** Oncotype Dx tests are not recorded in this data item. See the following data items for Oncotype Dx. * Oncotype Dx Recurrence Score-DCIS [NAACCR Data Item #3903] * Oncotype Dx Recurrence Score-Invasive [NAACCR Data Item #3904] * Oncotype Dx Risk Level-DCIS [NAACCR Data Item #3905] * Oncotype Dx Risk Level-Invasive [NAACCR Data Item #3906]Default
8NAACCR Item
NAACCR #3894Metadata
SSDI| Code | Description |
|---|---|
| 1 | Mammaprint |
| 2 | PAM50 (Prosigna) |
| 3 | Breast Cancer Index |
| 4 | EndoPredict |
| 5 | Test performed, type of test unknown |
| 6 | Multiple tests, any tests in codes 1-4 |
| 7 | Test ordered, results not in chart |
| 8 | Not applicable: Information not collected for this case (If this item is required by your standard setter, use of code 8 will result in an edit error.) |
| 9 | Not documented in medical record Multigene Signature Method not assessed or unknown if assessed |