Summary Stage 2018: Vagina

Summary Stage 2018

Notes

**Vagina** 8000-8700, 8720-8790, 8933, 8980, 9071, 9110, 9700-9701 C529 C529 Vagina, NOS **Note 1:** The following sources were used in the development of this chapter * SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998) (https://seer.cancer.gov/archive/manuals/EOD10Dig.3rd.pdf) * SEER Summary Staging Manual-2000: Codes and Coding Instructions (https://seer.cancer.gov/tools/ssm/ssm2000/) * Collaborative Stage Data Collection System, version 02.05: https://cancerstaging.org/cstage/Pages/default.aspx * Chapter 51 *Vagina*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois. **Note 2:** See the following chapters for the listed histologies * 8710-8714, 8800-8932, 8934, 8940-8975, 8981-9070, 9072-9105, 9120-9137, 9141-9582: *Soft Tissue* * 8935-8936: *GIST* * 9140: *Kaposi Sarcoma* **Note 3:** Isolated tumor cells (ITCs) are defined as single tumor cells or small clusters not greater than 0.2 mm, usually detected by immunohistochemical (IHC) or molecular methods. ITCs do not usually show evidence of malignant activity (e.g., proliferation or stromal reaction). * Lymph nodes with ITCs only are **not** counted as positive nodes for Summary Stage

NAACCR Item

NAACCR #764
SS2018 Description
0 In situ: noninvasive, intraepithelial
1 Localized only (localized, NOS) - FIGO Stage I + Confined to vagina + Musculature involved + Submucosa (stroma) (vagina)
2 Regional by direct extension only - FIGO Stage II + Bladder wall or bladder, NOS (excluding mucosa) + Cervix + Cul de sac (rectouterine pouch) + Extension to lower third of the vagina (from proximal vagina) + "Frozen pelvis" (clinically diagnosed) + Hydronephrosis or nonfunctioning kidney + Parametrium + Paravaginal soft tissue + Pelvic wall * Fascia * Muscle * Neurovascular structures * Skeletal portions of bony pelvis + Rectal wall or rectum, NOS excluding mucosa + Rectovaginal septum + Vesicovaginal septum + Vulva
3 Regional lymph node(s) involved only - Lower third of vagina + Femoral [superficial inguinal] + Inguinal, NOS - Upper two thirds of vagina + Iliac (common, external, NOS) + Internal iliac (hypogastric) + Middle sacral (promontorial) (Gerota's node) + Obturator + Para-aortic + Parametrial + Pelvic, NOS + Presacral + Sacral - Regional lymph node(s), NOS + Lymph node(s), NOS
4 Regional by BOTH direct extension AND regional lymph node(s) involved - Codes (2) + (3)
7 Distant site(s)/lymph node(s) involved - Distant site(s) (including further contiguous extension) + FIGO Stage IVA * Bladder mucosa (excluding bullous edema) * Extension beyond true pelvis * Rectal mucosa * Urethra - Distant lymph node(s), NOS + All sites * Aortic (lateral [lumbar], para-aortic, periaortic, NOS) * Retroperitoneal, NOS + Lower third of vagina * Iliac (common, external, NOS) * Internal iliac (hypogastric) * Middle sacral (promontorial) (Gerota's node) * Obturator * Para-aortic * Parametrial * Pelvic, NOS * Presacral * Sacral * Superficial inguinal (femoral) + Upper two thirds of vagina * Inguinal, NOS - Distant metastasis, NOS + Carcinomatosis + Distant metastasis WITH or WITHOUT distant lymph node(s)
9 Unknown if extension or metastasis
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998 (2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001. (3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05.** American Joint Committee on Cancer (Chicago, IL) (4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging.** In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 3-30 (5) **Introduction to Female Reproductive Organs**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 631 (6) Gibb, R.K., Olawaiye, A.B., Mutch, D.G., et al. **Vagina**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 641-647