Summary Stage 2018: Corpus Carcinoma and Carcinosarcoma

Summary Stage 2018

Notes

**Corpus Carcinoma and Carcinosarcoma** 8000-8700, 8720-8790, 8950, 8980, 9700-9701 C540-C543, C548-C549, C559 C540 Isthmus uteri C541 Endometrium C542 Myometrium C543 Fundus uteri C548 Overlapping lesion of corpus uteri C549 Corpus uteri C559 Uterus, NOS **Note 1:** The following sources were used in the development of this chapter * SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998) (https://seer.cancer.gov/archive/manuals/EOD10Dig.3rd.pdf) * SEER Summary Staging Manual-2000: Codes and Coding Instructions (https://seer.cancer.gov/tools/ssm/ssm2000/) * Collaborative Stage Data Collection System, version 02.05: https://cancerstaging.org/cstage/Pages/default.aspx * Chapter 53 *Corpus Uteri-Carcinoma and Carcinosarcoma*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois. **Note 2:** See the following schemas for the listed histologies * 8710-8714, 8800-8941, 8951-8975, 8981-9137, 9141-9582: *Corpus Sarcoma* * 9140: *Kaposi Sarcoma* **Note 3:** Isolated tumor cells (ITCs) are defined as single tumor cells or small clusters not greater than 0.2 mm, usually detected by immunohistochemical (IHC) or molecular methods. ITCs do not usually show evidence of malignant activity (e.g., proliferation or stromal reaction). * Lymph nodes with ITCs only are **not** counted as positive nodes for Summary Stage

NAACCR Item

NAACCR #764
SS2018 Description
0 In situ, intraepithelial, noninvasive, preinvasive
1 Localized only (localized, NOS) - FIGO Stage IA + Invasion of inner half of myometrium - FIGO Stage IB + Invasion of outer half of myometrium - FIGO Stage I [NOS] + Confined to uterus, NOS + Invasion of myometrium, NOS + Invasive cancer confined to corpus uteri
2 Regional by direct extension only - FIGO Stage II + Cervix uteri, NOS + Cervical stromal invasion + Endocervical glandular involvement + Tumor invading the stromal connective tissue of the cervix but not extending beyond the uterus - FIGO Stage IIIA + Adnexa (direct extension or metastasis) + Fallopian tube(s) + Ovary(ies) + Serosa, NOS + Tunica serosa (visceral peritoneum of corpus, serosa covering the corpus) + Tunica serosa of corpus - FIGO Stage IIIB + Bladder, NOS (excluding mucosa) + Described clinically as "frozen pelvis", NOS + Ligaments (broad, round, uterosacral) + Parametrium, NOS + Parietal serosa of pelvic wall + Pelvic wall(s) + Peritoneal cytology positive for malignant cells + Rectal wall + Rectum, NOS excluding mucosa + Ureter + Vagina (direct extension or metastasis) + Visceral peritoneum of pelvic organs excluding serosa of corpus + Vulva - FIGO Stage III [NOS]
3 Regional lymph node(s) involved only - Aortic (lateral [lumbar], Periaortic, NOS) - Iliac (external, internal [hypogastric], NOS) - Lateral (laterosacral) - Middle (promontorial) (Gerota's node) - Obturator - Para-aortic - Paracervical - Parametrial - Pelvic, NOS - Presacral - Sacral - Uterosacral - Regional lymph node(s), NOS + Lymph node(s), NOS
4 Regional by BOTH direct extension AND regional lymph node(s) involved - Codes (2) + (3)
7 Distant site(s)/lymph node(s) involved - Distant site(s) (including further contiguous extension) + FIGO Stage IVA * Abdominal serosa (visceral or parietal peritoneum of abdomen) * Bladder mucosa (excluding bullous edema) * Bowel mucosa * Cul de sac (rectouterine pouch or Pouch of Douglas) * Sigmoid colon * Small intestine + FIGO Stage IVB * Bone * Intraperitoneal disease * Liver * Lung + FIGO Stage IV [NOS] - Distant lymph node(s), NOS + Deep inguinal, NOS * Node of Cloquet or Rosenmuller (highest deep inguinal) + Inguinal, NOS + Superficial inguinal (femoral) - Distant metastasis, NOS + Carcinomatosis + Distant metastasis WITH or WITHOUT distant lymph node(s)
9 Unknown if extension or metastasis
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998 (2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001. (3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05.** American Joint Committee on Cancer (Chicago, IL) (4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging.** In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 3-30 (5) **Introduction to Female Reproductive Organs**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 631 (6) Powell, M.A., Olawaiye, A.B., Mutch, D.G., et al. **Corpus Uteri - Carcinoma and Carcinosarcoma**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 661-669