EOD Primary Tumor

This input is used for staging


**Note 1:** The following histologies can be localized (code 100), systemic (700) or unknown (999) 9740 Mast cell sarcoma 9751 Langerhans cell histiocytosis, disseminated 9755 Histiocytic sarcoma 9756 Langerhans cell sarcoma 9757 Interdigitating dendritic cell sarcoma 9758 Follicular dendritic cell sarcoma 9759 Fibroblastic reticular cell tumor 9930 Myeloid sarcoma 9971 Polymorphic PTLD **Note 2:** For histologies listed in **Note 1**, it is possible to have lymph node involvement; however, at this time, lymph node involvement for these histologies is not collected. **Note 3:** **The following histologies are systemic (code 700):** 9591 Splenic B-cell lymphoma/leukemia, unclassifiable 9724 Systemic EBV-positive T-cell lymphoma of childhood 9727 Blastic plasmacytoid dendritic cell neoplasm 9740 Mast cell sarcoma 9741 Systemic mastocytosis with an associated hematological neoplasm 9742 Mast cell leukemia 9762 Heavy chain diseases 9800 Leukemia, NOS 9801 Acute undifferentiated leukemia 9806 Mixed-phenotype acute leukemia with t(9;22)(q34.1;q11.2); *BCR-ABL1* 9807 Mixed-phenotype acute leukemia with t(v;11q23.3); *KMT2A*-rearranged 9808 Mixed -phenotype acute leukemia, B/myeloid, NOS 9809 Mixed-phenotype acute leukemia, T/myeloid, NOS 9811 B-lymphoblastic leukemia/lymphoma, NOS 9812 B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2); *BCR-ABL1* 9813 B-lymphoblastic leukemia/lymphoma with t(v;11q23.3); *KMT2A*-rearranged 9814 B-lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1); *ETV6-RUNX1* 9815 B-lymphoblastic/lymphoma with hyperdiploidy 9816 B-lymphoblastic/lymphoma with hypodiploidy (hypodiploid ALL) 9817 B-lymphoblastic/lymphoma with t(5;14)(q31.1;q32.1); IGH/*IL3* 9818 B-lymphoblastic/lymphoma with t(1;19)(q23;p13.3); *TCF3-PBX1* 9820 Lymphoid leukemia, NOS 9831 T-cell large granular lymphocytic leukemia 9832 Prolymphocytic leukemia, NOS 9833 B-cell prolymphocytic leukemia 9834 T-cell prolymphocytic leukemia 9837 T-lymphoblastic leukemia/lymphoma 9840 Pure erythroid leukemia 9860 Myeloid leukemia, NOS 9861 Acute myeloid leukemia, NOS 9863 Chronic myeloid leukemia 9865 Acute myeloid leukemia with t(6;9)(p23;q34.1); *DEK-NUP214* 9866 Acute promyelocytic leukemia with *PML-RARA* 9867 Acute myelomonocytic leukemia 9869 Acute myeloid leukemia with inv(3)(q21.3q26.2) or t(3;3)(q21.3;q26;2); *RBM15-MKL1* 9870 Acute basophilic leukemia 9871 Acute myeloid leukemia with inv(16)(p13.1q22) or t(16;16)(p13.1;q22); *CBFB-MYH11* 9872 Acute myeloid leukemia, minimal differentiation 9873 Acute myeloid leukemia without maturation 9874 Acute myeloid leukemia with maturation 9875 Chronic myeloid leukemia, *BCR-ABL1*-positive 9876 Atypical chronic myeloid leukemia *BCR-ABL1*-negative 9891 Acute monoblastic and monocytic leukemia 9895 Acute myeloid leukemia with myelodysplasia-related changes 9896 Acute myeloid leukemia with t(8;21)(q22;q22.1), *RUNX1-RUNX1T1* 9897 Acute myeloid leukemia with t(9;11)(p21.3;q23.3); *KMT2A-MLLT3* 9898 Myeloid leukemia associated with Down Syndrome 9910 Acute megakaryoblastic leukemia 9911 Acute myeloid leukemia (megakaryoblastic) with t(1;22)(p13.3;q13.1); *RBM15-MKL1* 9920 Therapy-related myeloid neoplasms 9931 Acute panmyelosis with myelofibrosis 9940 Hairy cell leukemia 9945 Chronic myelomonocytic leukemia, NOS 9946 Juvenile myelomonocytic leukemia 9948 Aggressive NK-cell leukemia 9950 Polycythemia vera 9961 Primary myelofibrosis 9962 Essential thrombocythemia 9963 Chronic neutrophilic leukemia 9964 Chronic eosinophilic leukemia, NOS 9965 Myeloid/lymphoid neoplasms with *PDGFRA* rearrangement 9966 Myeloid/lymphoid neoplasm with *PDGFRB* rearrangement 9967 Myeloid/lymphoid neoplasm with *FGFR1* rearrangement 9975 Myelodysplastic/myeloproliferative neoplasm, unclassifiable 9980 Myelodysplastic syndrome with single lineage dysplasia 9982 Myelodysplastic syndrome with ring sideroblasts and single lineage dysplasia 9983 Myelodysplastic syndrome with excess blasts 9985 Myelodysplastic syndrome with multilineage dysplasia 9986 Myelodysplastic syndrome with isolated del(5q) 9989 Myelodysplastic syndrome, unclassifiable 9991 Refractory neutropenia 9992 Refractory thrombocytopenia




Code Description SS2018 T
100 Localized disease (Single/solitary/unifocal/isolated) See Notes 1 and 2 L
700 Systemic disease See Note 3 D
999 Unknown; extension not stated Primary tumor cannot be assessed Not documented in patient record Death Certificate Only U
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998 (2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001. (3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05**. American Joint Committee on Cancer (Chicago, IL) (4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 3-30 (5) **Introduction to Hematologic Malignancies**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 931-935 (6) Radich, J.P., Jaffe, E.S., Leonard, J.P., et al. **Leukemia**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 979-997