EOD Primary Tumor

This input is used for staging


**Note 1:** The biliary radicals are the ducts or tubes that drain bile into the intestine as part of the digestive process. The second-order biliary radicals are the next largest branches or ducts of the biliary system which join to form or empty into the main hepatic bile duct. **Note 2:** Codes 400 and 500 are defined strictly in terms of invasion into specific large blood vessels and the biliary radicals within the liver. Code 500 when the specified vessels and/or the biliary radical within the liver plus other named organs are involved. **Note 3:** Involvement within the porta hepatis is coded according to the structures involved: portal vein, common hepatic artery, and common hepatic duct.




Code Description SS2018 T
000 In situ, intraepithelial, noninvasive High-grade biliary intraepithelial neoplasia (BilIn-3) IS
100 Invasive tumor of perihilar (proximal) bile duct(s) confined to - Lamina propria - Mucosa, NOS - Muscle layer of fibrous tissue - Muscularis propria - Subepithelial connective tissue (tunica mucosa) - Submucosa (superficial invasion) Confined to perihilar bile duct, NOS Localized, NOS L
200 Adipose tissue Adjacent (connective) tissue, NOS Beyond wall of bile duct Periductal/fibromuscular connective tissue RE
250 Adjacent hepatic parenchyma Liver RE
300 Colon Duodenum Gallbladder Omentum (greater, lesser, NOS) Pancreas Stomach RE
400 Unilateral branches of hepatic artery (right or left) Unilateral branches of portal vein (right or left) RE
500 Hepatic artery (common, NOS) Main portal vein or its branches bilaterally Portal vein, NOS Second-order biliary radicals bilaterally Unilateral second-order biliary radicals with contralateral portal vein or hepatic artery involvement RE
600 Abdominal wall D
700 Further contiguous extension D
800 No evidence of primary tumor U
999 Unknown; extension not stated Primary tumor cannot be assessed Not documented in patient record Death Certificate Only U
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998 (2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001. (3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05**. American Joint Committee on Cancer (Chicago, IL) (4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 3-30 (5) Nagorney, D.M., Pawlik, T.M., Vauthey, J.N., et al. **Perihilar Bile Ducts**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 311-316