Grade Post Therapy


**Note 1:** Leave post-therapy grade blank when * No neoadjuvant therapy * Clinical or pathological case only * There is only one grade available and it cannot be determined if it is clinical, pathological or post-therapy **Note 2:** Assign the highest grade from the resected primary tumor assessed after the completion of neoadjuvant therapy. **Note 3:** Codes 1-5 take priority over A-E. **Note 4:** Code 9 when * Surgical resection is done after neoadjuvant therapy and grade from the primary site is not documented * Grade checked “not applicable” on CAP Protocol (if available) and no other grade information is available **Note 5:** If you are assigning an AJCC 8th edition stage group * Grade is required to assign stage group * Codes A-E are treated as an unknown grade when assigning AJCC stage group * An unknown grade may result in an unknown stage group


NAACCR #3845


Code Description
1 Grade Group 1: Gleason score less than or equal to 6
2 Grade Group 2: Gleason score 7 Gleason pattern 3+4
3 Grade Group 3: Gleason score 7 Gleason pattern 4+3
4 Grade Group 4: Gleason score 8
5 Grade Group 5: Gleason score 9 or 10
A Well differentiated
B Moderately differentiated
C Poorly differentiated
D Undifferentiated, anaplastic
E Stated as “Gleason score 7” with no patterns documented or Any Gleason patterns combination equal to 7 not specified in 2 or 3
9 Grade cannot be assessed; Unknown
<BLANK> See Note 1