Summary Stage 2018: Myeloma and Plasma Cell Disorders
Summary Stage 2018
Notes
**Myeloma and Plasma Cell Disorders**
9671 Lymphoplasmacytic lymphoma (except C441, C690, C695-C696)
9731 Plasmacytoma, NOS
9732 Plasma cell myeloma/multiple myeloma
9734 Plasmacytoma, extramedullary (except C441, C690, C695-C696)
9761 Waldenstrom Macroglobulinemia
**Note 1:** The following sources were used in the development of this chapter
* SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998) (https://seer.cancer.gov/archive/manuals/EOD10Dig.3rd.pdf)
* SEER Summary Staging Manual-2000: Codes and Coding Instructions (https://seer.cancer.gov/tools/ssm/ssm2000/)
* Collaborative Stage Data Collection System, version 02.05: https://cancerstaging.org/cstage/Pages/default.aspx
* Chapter 82 *Plasma Cell Myeloma and Plasma Cell Disorder*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois.
**Note 2:** Codes 0, 2, and 4 are not applicable for this chapter.
**Note 3:** Plasma cell myeloma/multiple myeloma (9732) is a widely disseminated plasma cell neoplasm, characterized by a single clone of plasma cells derived from B cells that grows in the bone marrow. It is always coded to 7 for systemic involvement.
**Note 4:** Lymphoplasmacytic lymphoma (9671) and Waldenstrom Macroglobulinemia (9761) are now collected with the plasma cell disorders. These are systemic diseases and should always be coded 7.
| SS2018 |
Description |
| 1 |
Localized only
- Single plasmacytoma occurring in bone (osseous or medullary) (9731)
+ WITH or WITHOUT soft tissue extension
- Single plasmacytoma, NOS (9734)
+ Single plasmacytoma occurring outside of bone (extraosseous or extramedullary) (9731) |
| 3 |
Regional lymph node(s) involved only
- Extraosseous plasmacytomas only (9734)
+ Regional lymph node(s), NOS
* Lymph node(s), NOS |
| 7 |
Distant site(s)/lymph node(s) involved
- Lymphoplasmacytic lymphoma (9671)
- Plasmacytomas (9731, 9734)
+ Multiple extraosseous or extramedullary plasmacytomas (9734)
+ Multiple osseous or medullary plasmacytomas (9731)
+ Multiple plasmacytomas, NOS (9731, 9734)
- Plasma cell myeloma (9732)
+ Multiple myeloma
+ Myeloma, NOS
- Waldenstrom Macroglobulinemia (9761) |
| 9 |
Unknown if extension or metastasis (applicable for 9731 and 9734 only) |
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998
(2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001.
(3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05**. American Joint Committee on Cancer (Chicago, IL)
(4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 3-30
(5) **Introduction to Hematologic Malignancies**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 931-935
(6) Bergsagel, P.L., Jaffe, E.S., Leonard, J.P., et al. **Plasma Cell Myeloma and Plasma Cell Disorders**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 973-977
