Summary Stage 2018: Adrenal Gland
Summary Stage 2018
Notes
**Adrenal Gland**
8000-8700, 8720-8790, 9700-9701
C740-C741, C749, C755
C740 Cortex of adrenal gland
C741 Medulla of adrenal gland
C749 Adrenal gland, NOS
C755 Aortic body and other paraganglioma (*Histologies 8680, 8690, 8692-8693, 8700 only*)
**Note 1:** The following sources were used in the development of this chapter
* SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998) (https://seer.cancer.gov/archive/manuals/EOD10Dig.3rd.pdf)
* SEER Summary Staging Manual-2000: Codes and Coding Instructions (https://seer.cancer.gov/tools/ssm/ssm2000/)
* Collaborative Stage Data Collection System, version 02.05: https://cancerstaging.org/cstage/Pages/default.aspx
* Chapter 76 *Adrenal Cortical Carcinoma*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois.
* Chapter 77 *Adrenal-Neuroendocrine Tumors*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois.
**Note 2:** See the following chapters for the listed histologies
* 8710-8714, 8800-8934, 8940-9137, 9141-9582: *Soft Tissue*
* 8935-8936: *GIST*
* 9140: *Kaposi Sarcoma*
| SS2018 |
Description |
| 0 |
In situ: noninvasive, intraepithelial |
| 1 |
Localized only (localized, NOS)
- Confined to adrenal gland, no extra-adrenal invasion |
| 2 |
Regional by direct extension only
- Adjacent connective tissue
- Gerota’s fascia
- Invasion of adjacent organs
+ Blood vessels (large)
* Renal vein
* Vena cava
+ Kidney
+ Retroperitoneal structures including
* Great vessels (aorta, inferior vena cava) |
| 3 |
Regional lymph node(s) involved only
- Aortic, NOS
+ Para-aortic
+ Periaortic
- Pericaval, NOS
+ Paracaval
+ Precaval
+ Retrocaval
- Retroperitoneal, NOS
- Regional lymph node(s), NOS
+ Lymph node(s), NOS |
| 4 |
Regional by BOTH direct extension AND regional lymph node(s) involved
- Codes (2) + (3) |
| 7 |
Distant site(s)/lymph node(s) involved
- Distant site(s) (including further contiguous extension)
+ Bone
+ Diaphragm
+ Liver
+ Lung
+ Pancreas
+ Spleen
- Distant lymph node(s), NOS
- Distant metastasis, NOS
+ Carcinomatosis
+ Distant metastasis WITH or WITHOUT distant lymph node(s) |
| 9 |
Unknown if extension or metastasis |
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998
(2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001.
(3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05.** American Joint Committee on Cancer (Chicago, IL)
(4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging.** In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 3-30
(5) Phan, A.T., Perrier, N.D., et al. **Adrenal Cortical Carcinoma**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 911-918
(6) Jimenez, C., Perrier, N.D., et al. **Adrenal – Neuroendocrine Tumors**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 919-927
