Extranodal Extension Head and Neck Pathological


**Note 1:** Physician statement of extranodal extension (ENE) pathologically during a lymph node dissection or physician pathological stage indicating the absence or presence of ENE can be used to code this data item when no other information is available. **Note 2:** Code the status of ENE assessed on histopathologic examination of surgically resected involved regional lymph node(s). Do not code ENE from a lymph node biopsy (FNA, core, incisional, excisional, sentinel). Do not code ENE for any distant lymph nodes. **Note 3:** Be aware that the rules for coding ENE for head and neck sites compared to non-head and neck sites are different. **Note 4:** Definitions of ENE subtypes and rules: * Microscopic ENE [ENE (mi)] is defined as less than or equal to 2 mm. * Major ENE [ENE (ma)] is defined as greater than 2 mm. * Both ENE (mi) and ENE (ma) qualify as ENE (+) for definition of pN. **Note 5:** The measurement of ENE is the distance from the lymph node capsule in millimeters (mm).




NAACCR #3832


Code Description
0.0 Lymph nodes positive for cancer but ENE not identified or negative
0.1-9.9 ENE 0.1 to 9.9 mm
X.1 ENE 10 mm or greater
X.2 ENE microscopic, size unknown Stated as ENE (mi)
X.3 ENE major, size unknown Stated as ENE (ma)
X.4 ENE present, microscopic or major unknown, size unknown
X.7 Surgically resected regional lymph node(s) negative for cancer (pN0)
X.8 Not applicable: Information not collected for this case (If this information is required by your standard setter, use of code X.8 may result in an edit error)
X.9 Not documented in medical record No surgical resection of regional lymph node(s) ENE not assessed pathologically, or unknown if assessed Pathological assessment of lymph node(s) not done, or unknown if done