Multigene Signature Result
Notes
**Note 1:** Physician statement of the Multigene Signature Results can be used to code this data item. **Note 2:** Multigene signatures or classifiers are assays of a panel of genes from a tumor specimen, intended to provide a quantitative assessment of the likelihood of response to chemotherapy and to evaluate prognosis or the likelihood of future metastasis. **Note 3:** Code the score or risk for the test performed. The same test should be used to record information in Multigene Signature Method [NAACCR Data Item # 3894]. **Note 4:** Oncotype Dx tests are not recorded in this data item. See the following data items for Oncotype Dx. * Oncotype Dx Recurrence Score-DCIS [NAACCR Data Item # 3903] * Oncotype Dx Recurrence Score-Invasive [NAACCR Data Item # 3904] * Oncotype Dx Risk Level-DCIS [NAACCR Data Item # 3905] * Oncotype Dx Risk Level-Invasive [NAACCR Data Item # 3906] **Note 5:** PAM50 (Prosigna) is a single numeric score of 1-100. If the score is available, record the score. If only the risk level is available, record that. **Note 6:** For Mammaprint, EndoPredict, and Breast Cancer Index, only record the risk level.Default
X8NAACCR Item
NAACCR #3895Metadata
SSDI| Code | Description | 
|---|---|
| 00-99 | Enter actual recurrence score Note: Depending on the test, the range of values may be different | 
| X1 | Score 100 | 
| X2 | Low risk | 
| X3 | Moderate [intermediate] risk | 
| X4 | High risk | 
| X7 | Test done, results not in chart | 
| X8 | Not applicable: Information not collected for this case (If this item is required by your standard setter, use of code X8 will result in an edit error.) | 
| X9 | Not documented in medical record Multigene Signature Results not assessed or unknown if assessed |