Grade Pathological

This input is used for staging


**Note 1:** Pathological grade must not be blank. **Note 2:** Assign the highest grade from the primary tumor. If the clinical grade is higher than the grade determined during the pathological time frame, use the grade that was identified during the clinical time frame for both the clinical grade and the pathological grade. **Note 3:** Codes 1-5 take priority over A-E. **Note 4:** Code 9 when * Grade from primary site is not documented * No resection of the primary site * Neo-adjuvant therapy is followed by a resection (see post-therapy grade) * Clinical case only (see clinical grade) * There is only one grade available and it cannot be determined if it is clinical, pathological, or after neo-adjuvant therapy * Grade checked “not applicable” on CAP Protocol (if available) and no other grade information is available **Note 5:** If you are assigning an AJCC 8th edition stage group * Grade is required to assign stage group * Codes A-E are treated as an unknown grade when assigning AJCC stage group * An unknown grade may result in an unknown stage group




NAACCR #3844


Code Description
1 Grade Group 1: Gleason score less than or equal to 6
2 Grade Group 2: Gleason score 7 Gleason pattern 3+4
3 Grade Group 3: Gleason score 7 Gleason pattern 4+3
4 Grade Group 4: Gleason score 8
5 Grade Group 5: Gleason score 9 or 10
A Well differentiated
B Moderately differentiated
C Poorly differentiated
D Undifferentiated, anaplastic
E Stated as “Gleason score 7” with no patterns documented or Any Gleason patterns combination equal to 7 not specified in 2 or 3
9 Grade cannot be assessed; Unknown