Grade Clinical

This input is used for staging


**Note 1:** Clinical grade must not be blank. **Note 2:** Assign the highest grade from the primary tumor assessed during the clinical time frame. **Note 3:** Codes 1-5 take priority over A-E. **Note 4:** Code 9 when * Grade from primary site is not documented * Clinical workup is not done (for example, cancer is an incidental finding during surgery for another condition) * Grade checked “not applicable” on CAP Protocol (if available) and no other grade information is available **Note 5:** If there is only one grade available and it cannot be determined if it is clinical, pathological, or after neo-adjuvant therapy, assign as a clinical grade and code unknown (9) for pathological grade, and blank for post-therapy grade. **Note 6:** If you are assigning an AJCC 8th edition stage group * Grade is required to assign stage group * Codes A-E are treated as an unknown grade when assigning AJCC stage group * An unknown grade may result in an unknown stage group




NAACCR #3843


Code Description
1 Grade Group 1: Gleason score less than or equal to 6
2 Grade Group 2: Gleason score 7 Gleason pattern 3+4
3 Grade Group 3: Gleason score 7 Gleason pattern 4+3
4 Grade Group 4: Gleason score 8
5 Grade Group 5: Gleason score 9 or 10
A Well differentiated
B Moderately differentiated
C Poorly differentiated
D Undifferentiated, anaplastic
E Stated as “Gleason score 7” with no patterns documented or Any Gleason patterns combination equal to 7 not specified in 2 or 3
9 Grade cannot be assessed; Unknown