Summary Stage 2018: Myeloma and Plasma Cell Disorders

Summary Stage 2018

Notes

**Myeloma and Plasma Cell Disorders** 9671 Lymphoplasmacytic lymphoma (except C441, C690, C695-C696) 9731 Plasmacytoma, NOS 9732 Plasma cell myeloma/multiple myeloma 9734 Plasmacytoma, extramedullary (except C441, C690, C695-C696) 9761 Waldenstrom Macroglobulinemia **Note 1:** The following sources were used in the development of this chapter * SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998) (https://seer.cancer.gov/archive/manuals/EOD10Dig.3rd.pdf) * SEER Summary Staging Manual-2000: Codes and Coding Instructions (https://seer.cancer.gov/tools/ssm/) * Collaborative Stage Data Collection System, version 02.05: https://cancerstaging.org/cstage/Pages/default.aspx * Chapter 82 *Plasma Cell Myeloma and Plasma Cell Disorder*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois. **Note 2:** Codes 0, 2, and 4 are not applicable for this chapter. **Note 3:** Plasma cell myeloma/multiple myeloma (9732) is a widely disseminated plasma cell neoplasm, characterized by a single clone of plasma cells derived from B cells that grows in the bone marrow. It is always coded to 7 for systemic involvement. **Note 4:** Lymphoplasmacytic lymphoma (9671) and Waldenstrom Macroglobulinemia (9761) are now collected with the plasma cell disorders. These are systemic diseases and should always be coded 7.

NAACCR Item

NAACCR #764
SS2018 Description
1 Localized only - Single plasmacytoma occurring in bone (osseous or medullary) (9731) + WITH or WITHOUT soft tissue extension - Single plasmacytoma, NOS (9734) + Single plasmacytoma occurring outside of bone (extraosseous or extramedullary) (9731)
3 Regional lymph node(s) involved only - Extraosseous plasmacytomas only (9734) + Regional lymph node(s), NOS * Lymph node(s), NOS
7 Distant site(s)/lymph node(s) involved - Lymphoplasmacytic lymphoma (9671) - Plasmacytomas (9731, 9734) + Multiple extraosseous or extramedullary plasmacytomas (9734) + Multiple osseous or medullary plasmacytomas (9731) + Multiple plasmacytomas, NOS (9731, 9734) - Plasma cell myeloma (9732) + Multiple myeloma + Myeloma, NOS - Waldenstrom Macroglobulinemia (9761)
9 Unknown if extension or metastasis (applicable for 9731 and 9734 only)
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998 (2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001. (3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05**. American Joint Committee on Cancer (Chicago, IL) (4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 3-30 (5) **Introduction to Hematologic Malignancies**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 931-935 (6) Bergsagel, P.L., Jaffe, E.S., Leonard, J.P., et al. **Plasma Cell Myeloma and Plasma Cell Disorders**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 973-977