Grade Pathological
Notes
**Note 1:** Pathological grade must not be blank.
**Note 2:** Assign the highest grade from the primary tumor. If the clinical grade is higher than the grade determined during the pathological time frame, use the grade that was identified during the clinical time frame for both the clinical grade and the pathological grade.
**Note 3:** Codes L and H take priority over A-D.
**Note 4:** Code 9 when
* Grade from primary site is not documented
* No resection of the primary site
* Neo-adjuvant therapy is followed by a resection (see post-therapy grade)
* Clinical case only (see clinical grade)
* There is only one grade available and it cannot be determined if it is clinical, pathological, or after neo-adjuvant therapy
* Grade checked “not applicable” on CAP Protocol (if available) and no other grade information is available
Default
9
Metadata
SSDI
| Code |
Description |
| L |
LG: Low grade: round monomorphic nuclei with only mild to moderate nuclear size variation, indistinct nucleoli, and chromatin characteristics resembling those of normal parathyroid or of adenoma |
| H |
HG: High grade: more pleomorphism, with a nuclear size variation greater than 4:1; prominent nuclear membrane irregularities; chromatin alterations, including hyperchromasia or margination of chromatin; and prominent nucleoli. High-grade tumors show several discrete confluent areas with nuclear changes |
| A |
Well differentiated |
| B |
Moderately differentiated |
| C |
Poorly differentiated |
| D |
Undifferentiated, anaplastic |
| 9 |
Grade cannot be assessed (GX); Unknown |
