Grade Post Therapy


**Note 1:** Leave post-therapy grade blank when * No neoadjuvant therapy * Clinical or pathological case only * There is only one grade available and it cannot be determined if it is clinical, pathological or post-therapy **Note 2:** Grade is applicable for the follicular lymphomas only (9690/3, 9691/3, 9695/3, 9698/3). For all other lymphoma histologies, code 9. **Note 3:** Assign the highest grade from the resected primary tumor assessed after the completion of neoadjuvant therapy. **Note 4:** Follicular lymphoma grade is based on the absolute number of centroblasts per high-power (40 x objective, 0.159 square mm) microscopic field (HPF). **Note 5:** Codes 1-5 take priority over L. **Note 6:** Code 9 when * Surgical resection is done after neoadjuvant therapy and grade from the primary site is not documented * Grade checked “not applicable” on CAP Protocol (if available) and no other grade information is available


NAACCR #3845


Code Description
1 G1: 0–5 centroblasts per HPF
2 G2: 6-15 centroblasts per HPF
3 G3: > 15 centroblasts
4 G3A: >15 centroblasts per HPF and centrocytes present
5 G3B: > 15 centroblasts per HPF and solid sheets of centroblasts
L Low grade: Grade 1-2
9 Grade cannot be assessed (GX); Unknown Not a follicular histology (9690/3, 9691/3, 9695/3, 9698/3)
<BLANK> See Note 1