Summary Stage 2018: Cervix
Summary Stage 2018
Notes
**Cervix**
8000-8700, 8720-8790, 8805, 8933, 8980, 9110, 9581, 9700-9701
C530-C531, C538-C539
C530 Endocervix
C531 Exocervix
C538 Overlapping lesion of cervix
C539 Cervix uteri
**Note 1:** The following sources were used in the development of this chapter
* SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998) (https://seer.cancer.gov/archive/manuals/EOD10Dig.3rd.pdf)
* SEER Summary Staging Manual-2000: Codes and Coding Instructions (https://seer.cancer.gov/tools/ssm/)
* Collaborative Stage Data Collection System, version 02.05: https://cancerstaging.org/cstage/Pages/default.aspx
* Chapter 52 *Cervix Uteri*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois.
**Note 2:** See the following chapters for the listed histologies
* 8710-8714, 8800-8804, 8806-8932, 8934, 8940-8975, 8981-9105, 9120-9137, 9141-9580, 9582: *Soft Tissue*
* 8935-8936: *GIST*
* 9140: *Kaposi Sarcoma*
**Note 3:** Para-aortic nodes are now regional instead of distant.
| SS2018 |
Description |
| 0 |
In situ, intraepithelial, noninvasive
- Cancer in situ WITH endocervical gland involvement
- Cervical intraepithelial neoplasia (CIN) Grade III
- Preinvasive |
| 1 |
Localized only (localized, NOS)
- FIGO Stage IA1
+ Measured stromal invasion 3.0 mm or less and 7.0 mm or less in horizontal spread
- FIGO Stage IA2
+ Measured stromal invasion 3.1 mm to 5.0 mm with a horizontal spread of 7.0 mm or less
- FIGO Stage IA [NOS]
+ Measured stromal invasion 5.0 mm or less measured from the base of the epithelium AND horizontal spread of 7.0 mm or less
- FIGO Stage IB
- FIGO Stage I [NOS]
+ Clinically visible lesion (macroscopic), including superficial invasion
+ Confined to cervix uteri or uterus, NOS, except corpus uteri, NOS
* (Not clinically visible or unknown if clinically visible) |
| 2 |
Regional by direct extension only
- FIGO Stage IIA, IIB, II [NOS]
+ Confined to corpus uteri, size, depth and horizontal spread unknown
+ Corpus uteri, NOS
+ Cul de sac (rectouterine pouch)
+ Invasion beyond uterus, NOS
+ Ligament(s) (broad, cardinal, uterosacral)
+ Parametrial (paracervical soft tissue) invasion
+ Upper two-thirds of vagina including fornices
+ Vagina, NOS
+ Vaginal wall, NOS
- FIGO Stage IIIA
+ Bladder wall
+ Bladder, NOS excluding mucosa
+ Bullous edema of bladder mucosa
+ Lower third of vagina
+ Rectal wall
+ Rectum, NOS excluding mucosa
+ Ureter, intra- and extramural
+ Vagina, lower third (not extending to pelvic wall)
+ Vulva
- FIGO Stage IIIB
+ Described clinically as frozen pelvis
+ Hydronephrosis or nonfunctioning kidney
+ Pelvic wall(s)
- FIGO Stage III [NOS]
+ Fallopian tube(s)
+ Ovary(ies)
+ Urethra |
| 3 |
Regional lymph node(s) involved only
- Aortic
+ Lateral aortic
+ Para-aortic
+ Periaortic
- Iliac, NOS
+ Common
+ External
+ Internal (hypogastric) (obturator), NOS
- Paracervical
- Parametrial
- Pelvic, NOS
- Sacral, NOS
+ Lateral (laterosacral)
+ Middle (promontorial) (Gerota’s node)
+ Presacral
+ Uterosacral
- Regional lymph node(s), NOS
+ Lymph node(s), NOS |
| 4 |
Regional by BOTH direct extension AND regional lymph node(s) involved
- Codes (2) + (3) |
| 7 |
Distant site(s)/lymph node(s) involved
- Distant site(s) (including further contiguous extension)
+ Bladder mucosa
+ Rectal mucosa
+ Sigmoid colon
+ Small intestine
+ FIGO Stage IVA, IVB, IV [NOS]
- Distant lymph node(s), NOS
+ Inguinal
+ Mediastinal
+ Scalene
+ Supraclavicular
- Distant metastasis, NOS
+ Carcinomatosis
+ Distant metastasis WITH or WITHOUT distant lymph node(s) |
| 9 |
Unknown if extension or metastasis |
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998
(2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001.
(3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05.** American Joint Committee on Cancer (Chicago, IL)
(4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging.** In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 3-30
(5) **Introduction to Female Reproductive Organs**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 631
(6) Erickson, B.A., Olawaiye, A.B., Mutch, D.G., et al. **Cervix Uteri**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 649-659
