HER2 Overall Summary

This input is used for staging


**Note 1:** Physician statement of HER2 Overall Summary can be used to code this data item when no other information is available. **Note 2:** The result of the HER2 test performed on the primary breast tissue is to be recorded in this data item. **Note 3:** Results from nodal or metastatic tissue may be used ONLY when there is no evidence of primary tumor. **Note 4:** In cases where HER2 is reported on more than one breast tumor specimen, record the highest value. If any sample is positive, record as positive. * ***Exception:*** If HER2 is positive on an in situ specimen and HER2 is negative on all tested invasive specimens, code HER2 as negative (code 0). **Note 5:** If neoadjuvant therapy is given, record the assay from tumor specimens prior to neoadjuvant therapy. * If neoadjuvant therapy is given and there are no HER2 results from pre-treatment specimens, report the findings from post-treatment specimens. **Note 6:** If the patient is HER2 positive and node negative, a multigene test such as Oncotype Dx may be performed, in which case another HER2 test will be performed. Do not record the results of that test in this field. * Record only the results of the test which made the patient eligible to be given the multigene test.




NAACCR #3855


Code Description
0 HER2 negative; equivocal
1 HER2 positive
7 Test ordered, results not in chart
9 Not documented in medical record Cannot be determined (indeterminate) HER2 Overall Summary status not assessed or unknown if assessed