Tumor Growth Pattern
**Note 1:** Physician statement of tumor growth pattern can be used to code this data item when no other information is available.
**Note 2:** Cholangiocarcinoma may be classified by growth pattern. The tumor growth patterns of intrahepatic cholangiocarcinoma include the mass forming type, the periductal infiltrating type, and a mixed type. The periductal infiltrating type of cholangiocarcinoma demonstrates a diffuse longitudinal growth pattern along the bile duct. Limited analyses suggest that the diffuse periductal infiltrating type is associated with a poor prognosis.
**Note 3:** Record the presence or absence of an infiltrating periductal component. This information may be obtained from radiology, surgery, or pathology reports.