Summary Stage 2018: Vagina

Summary Stage 2018

Notes

**Vagina** C529 C529 Vagina, NOS **Note:** The following sources were used in the development of this schema * SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998) (https://seer.cancer.gov/archive/manuals/EOD10Dig.3rd.pdf) * SEER Summary Staging Manual-2000: Codes and Coding Instructions (https://seer.cancer.gov/tools/ssm/) * Collaborative Stage Data Collection System, version 02.05: https://cancerstaging.org/cstage/Pages/default.aspx * Chapter 51 *Vagina*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois.

NAACCR Item

NAACCR #764
SS2018 Description
0 In situ: noninvasive, intraepithelial
1 Localized only (localized, NOS) - FIGO Stage I + Confined to vagina + Musculature involved + Submucosa (stroma) (vagina)
2 Regional by direct extension only - FIGO Stage II + Bladder wall or bladder, NOS (excluding mucosa) + Cervix + Cul de sac (rectouterine pouch) + Extension to lower third of the vagina (from proximal vagina) + “Frozen pelvis” (clinically diagnosed) + Hydronephrosis or nonfunctioning kidney + Parametrium + Paravaginal soft tissue + Pelvic wall * Fascia * Muscle * Neurovascular structures * Skeletal portions of bony pelvis + Rectal wall or rectum, NOS excluding mucosa + Rectovaginal septum + Vesicovaginal septum + Vulva
3 Regional lymph node(s) involved only - Lower third of vagina + Femoral [superficial inguinal] + Inguinal, NOS - Upper two thirds of vagina + Iliac (common, external, NOS) + Internal iliac (hypogastric) + Middle sacral (promontorial) (Gerota’s node) + Obturator + Para-aortic + Parametrial + Pelvic, NOS + Presacral + Sacral - Regional lymph node(s), NOS + Lymph node(s), NOS
4 Regional by BOTH direct extension AND regional lymph node(s) involved - Codes (2) + (3)
7 Distant site(s)/lymph node(s) involved - Distant site(s) (including further contiguous extension) + FIGO Stage IVA * Bladder mucosa (excluding bullous edema) * Extension beyond true pelvis * Rectal mucosa * Urethra - Distant lymph node(s), NOS + All sites * Aortic (lateral [lumbar], para-aortic, periaortic, NOS) * Retroperitoneal, NOS + Lower third of vagina * Iliac (common, external, NOS) * Internal iliac (hypogastric) * Middle sacral (promontorial) (Gerota’s node) * Obturator * Para-aortic * Parametrial * Pelvic, NOS * Presacral * Sacral * Superficial inguinal (femoral) + Upper two thirds of vagina * Inguinal, NOS - Distant metastasis, NOS + Carcinomatosis + Distant metastasis WITH or WITHOUT distant lymph node(s)
9 Unknown if extension or metastasis
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998 (2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001. (3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05.** American Joint Committee on Cancer (Chicago, IL) (4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging.** In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 3-30 (5) **Introduction to Female Reproductive Organs**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 631 (6) Gibb, R.K., Olawaiye, A.B., Mutch, D.G., et al. **Vagina**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 641-647