Summary Stage 2018: Lymphoma
Summary Stage 2018
Notes
**Note 1:** The following sources were used in the development of this schema * SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998) (https://seer.cancer.gov/archive/manuals/EOD10Dig.3rd.pdf) * SEER Summary Staging Manual-2000: Codes and Coding Instructions (https://seer.cancer.gov/tools/ssm/) * Collaborative Stage Data Collection System, version 02.05: https://cancerstaging.org/cstage/Pages/default.aspx * Chapter 79 *Hodgkin and Non-Hodgkin Lymphomas*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois. * Chapter 80 *Pediatric Hodgkin and Non-Hodgkin Lymphomas*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois. **Note 2:** See the *Lymphoma-CLL/SLL* schema for Chronic lymphocytic leukemia/small lymphocytic lymphoma (9823). **Note 3:** The Cotswold modification of the Ann Arbor staging system (used in AJCC 6th and 7th editions) has been updated to the *Lugano classification*. The *Lugano classification* includes an E suffix for lymphoma with either localized extralymphatic presentations (Stage IE) or by contiguous spread from nodal disease (Stage IIE). A change from the Cotswold modification of the Ann Arbor Staging System, E lesions do not apply to patients with Stage III nodal disease; or any patient with nodal disease above and below the diaphragm with concurrent contiguous extralymphatic involvement (Stage IV), which was previously Stage IIIE. **Note 4:** Schema includes the preferred terms based on the *2017 WHO Classification of Haematopoietic and Lymphoid Tissues* 9590 Malignant lymphoma, NOS 9591 Non-Hodgkin lymphoma, NOS 9596 B-cell lymphoma, unclassifiable, with features intermediate between DLBCL and classic Hodgkin lymphoma 9597 Primary cutaneous follicle centre lymphoma 9650 Classical Hodgkin lymphoma 9651 Lymphocyte-rich classic Hodgkin lymphoma 9652 Mixed cellularity classic Hodgkin lymphoma 9653 Lymphocyte-depleted classic Hodgkin lymphoma 9659 Nodular lymphocyte predominant Hodgkin lymphoma 9663 Nodular sclerosis classic Hodgkin lymphoma 9673 Mantle cell lymphoma 9678 Primary effusion lymphoma 9679 Primary mediastinal (thymic) large B-cell lymphoma 9680 Diffuse large B-cell lymphoma (DLBCL) 9687 Burkitt lymphoma 9688 T-cell/histiocyte-rich large B-cell lymphoma 9689 Splenic marginal zone lymphoma 9690 Follicular lymphoma 9691 Follicular lymphoma, grade 2 9695 Follicular lymphoma, grade 1 9698 Follicular lymphoma, grade 3 9699 Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) 9702 Peripheral T-cell lymphoma, NOS 9705 Angioimmunoblastic T-cell lymphoma 9708 Subcutaneous panniculitis-like T-cell lymphoma 9709 Primary cutaneous peripheral T-cell lymphomas 9712 Intravascular large B-cell lymphoma 9714 Anaplastic large cell lymphoma, ALK-positive 9716 Hepatosplenic T-cell lymphoma 9717 Enteropathy-associated T-cell lymphoma 9718 Primary cutaneous anaplastic large cell lymphoma 9719 Extranodal NK/T-cell lymphoma, nasal type 9725 Hydroa vacciniforme-like lymphoma 9726 Primary cutaneous gamma-delta T-cell lymphoma 9735 Plasmablastic lymphoma 9737 ALK-positive large B-cell lymphoma 9738 HHV8-positive DLBCL, NOS 9823 Chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma 9826 Burkitt cell leukemia 9827 Adult T-cell leukemia/lymphomaNAACCR Item
NAACCR #764| SS2018 | Description |
|---|---|
| 1 | Localized only - Involvement of multiple nodal chains in the SAME lymph node region - Multifocal involvement of one extralymphatic organ/site (except lung/liver) WITHOUT nodal involvement - Single extralymphatic site WITHOUT nodal involvement - Single lymph node region involved |
| 2 | Regional, NOS - Bulky disease present - Contiguous extension between extralymphatic sites and regional nodes + WITH or WITHOUT involvement of other nodal regions on SAME side of diaphragm - Localized involvement of a single extralymphatic organ/site + WITH involvement of its regional lymph node(s) OR + WITH involvement of other lymph node(s) on the SAME side of the diaphragm - Two or more lymph node regions involved SAME side of diaphragm |
| 7 | Distant site(s)/lymph node(s) involved - Distant involvement + Diffuse or disseminated (multifocal) involvement of ONE extralymphatic organ/site * WITH associated lymph node involvement OR + Diffuse or disseminated (multifocal) involvement of ONE or MORE extralymphatic organ(s)/site(s) * WITH or WITHOUT associated lymph node involvement + Involvement of isolated extralymphatic organ in absence of involvement of adjacent lymph nodes, but in conjunction with disease in distant sites + Involvement of lymph node regions on BOTH sides of the diaphragm * OR nodes ABOVE the diaphragm involved WITH spleen involvement + Multifocal involvement of one extralymphatic organ/site WITH nodal involvement + Noncontiguous extralymphatic organ involvement in conjunction with nodal disease (two or more sites involved) - Distant metastasis, NOS + Bone marrow + Cerebrospinal fluid (CSF) + Liver + Lung (other than by direct extension in code 2) |
| 9 | Unknown if extension or metastasis |