Summary Stage 2018: Liver

Summary Stage 2018

Notes

**Liver** C220 Liver **Note:** The following sources were used in the development of this schema * SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998) (https://seer.cancer.gov/archive/manuals/EOD10Dig.3rd.pdf) * SEER Summary Staging Manual-2000: Codes and Coding Instructions (https://seer.cancer.gov/tools/ssm/) * Collaborative Stage Data Collection System, version 02.05: https://cancerstaging.org/cstage/Pages/default.aspx * Chapter 22 *Liver*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois.

NAACCR Item

NAACCR #764
SS2018 Description
0 In situ: noninvasive, intraepithelial
1 Localized only (localized, NOS) - Confined to liver, NOS - Single tumor (one lobe) + WITHOUT or UNKNOWN vascular invasion - Multiple (satellite) nodules/tumors (one lobe) + WITHOUT or UNKNOWN vascular invasion
2 Regional by direct extension only - Diaphragm - Extrahepatic bile duct(s) - Extrahepatic blood vessel(s) + Hepatic artery + Portal vein + Vena cava - Gallbladder - Lesser omentum - Ligament(s) + Coronary + Falciform + Hepatoduodenal + Hepatogastric + Round (of liver) + Triangular - Peritoneum, NOS + Parietal + Visceral - Major vascular invasion, NOS - More than one lobe involved by contiguous growth (single lesion) + WITH or WITHOUT vascular invasion - Multiple (satellite) nodules/ tumors in more than one lobe of liver or on surface of parenchyma + WITH or WITHOUT vascular invasion - Single lesion (one lobe) WITH vascular invasion
3 Regional lymph node(s) involved only - Caval - Hepatic, NOS + Hepatic artery + Hepatic pedicle + Inferior vena cava + Porta hepatis (portal) (hilar) [in hilus of liver]Hepatoduodenal ligament - Periportal - Portal vein - Regional lymph node(s), NOS + Lymph node(s), NOS
4 Regional by BOTH direct extension AND regional lymph node(s) involved - Codes (2) + (3)
7 Distant site(s)/lymph node(s) involved - Distant site(s) (including further contiguous extension) + Pancreas + Pleura + Stomach - Distant lymph node(s), NOS + Aortic (para-aortic, periaortic) + Cardiac + Coronary artery + Diaphragmatic, NOS + Inferior phrenic nodes + Lateral (aortic) (lumbar) + Pericardial (pericardiac) + Peripancreatic (near head of pancreas only) + Posterior mediastinal (tracheoesophageal) including juxtaphrenic nodes + Renal artery + Retroperitoneal, NOS - Distant metastasis, NOS + Carcinomatosis + Distant metastasis WITH or WITHOUT distant lymph node(s)
9 Unknown if extension or metastasis
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998 (2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001. (3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05**. American Joint Committee on Cancer (Chicago, IL) (4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 3-30 (5) Abou-Alfa, G.K., Pawlik, T.M., Vauthey, J.N., et al. **Liver**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 287-293