Summary Stage 2018: Cervix

Summary Stage 2018

Notes

**Cervix** C530-C531, C538-C539 C530 Endocervix C531 Exocervix C538 Overlapping lesion of cervix C539 Cervix uteri **Note 1:** The following sources were used in the development of this schema * SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998) (https://seer.cancer.gov/archive/manuals/EOD10Dig.3rd.pdf) * SEER Summary Staging Manual-2000: Codes and Coding Instructions (https://seer.cancer.gov/tools/ssm/) * Collaborative Stage Data Collection System, version 02.05: https://cancerstaging.org/cstage/Pages/default.aspx * Chapter 52 *Cervix Uteri*, in the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Used with permission of the American College of Surgeons, Chicago, Illinois. **Note 2:** Para-aortic nodes are now regional instead of distant.

NAACCR Item

NAACCR #764
SS2018 Description
0 In situ, intraepithelial, noninvasive - Cancer in situ WITH endocervical gland involvement - Cervical intraepithelial neoplasia (CIN) Grade III - Preinvasive
1 Localized only (localized, NOS) - FIGO Stage IA1 + Measured stromal invasion 3.0 mm or less and 7.0 mm or less in horizontal spread - FIGO Stage IA2 + Measured stromal invasion 3.1 mm to 5.0 mm with a horizontal spread of 7.0 mm or less - FIGO Stage IA [NOS] + Measured stromal invasion 5.0 mm or less measured from the base of the epithelium AND horizontal spread of 7.0 mm or less - FIGO Stage IB - FIGO Stage I [NOS] + Clinically visible lesion (macroscopic), including superficial invasion + Confined to cervix uteri or uterus, NOS, except corpus uteri, NOS * (Not clinically visible or unknown if clinically visible)
2 Regional by direct extension only - FIGO Stage IIA, IIB, II [NOS] + Confined to corpus uteri, size, depth and horizontal spread unknown + Corpus uteri, NOS + Cul de sac (rectouterine pouch) + Invasion beyond uterus, NOS + Ligament(s) (broad, cardinal, uterosacral) + Parametrial (paracervical soft tissue) invasion + Upper two-thirds of vagina including fornices + Vagina, NOS + Vaginal wall, NOS - FIGO Stage IIIA + Bladder wall + Bladder, NOS excluding mucosa + Bullous edema of bladder mucosa + Lower third of vagina + Rectal wall + Rectum, NOS excluding mucosa + Ureter, intra- and extramural + Vagina, lower third (not extending to pelvic wall) + Vulva - FIGO Stage IIIB + Described clinically as frozen pelvis + Hydronephrosis or nonfunctioning kidney + Pelvic wall(s) - FIGO Stage III [NOS] + Fallopian tube(s) + Ovary(ies) + Urethra
3 Regional lymph node(s) involved only - Aortic + Lateral aortic + Para-aortic + Periaortic - Iliac, NOS + Common + External + Internal (hypogastric) (obturator), NOS - Paracervical - Parametrial - Pelvic, NOS - Sacral, NOS + Lateral (laterosacral) + Middle (promontorial) (Gerota’s node) + Presacral + Uterosacral - Regional lymph node(s), NOS + Lymph node(s), NOS
4 Regional by BOTH direct extension AND regional lymph node(s) involved - Codes (2) + (3)
7 Distant site(s)/lymph node(s) involved - Distant site(s) (including further contiguous extension) + Bladder mucosa + Rectal mucosa + Sigmoid colon + Small intestine + FIGO Stage IVA, IVB, IV [NOS] - Distant lymph node(s), NOS + Inguinal + Mediastinal + Scalene + Supraclavicular - Distant metastasis, NOS + Carcinomatosis + Distant metastasis WITH or WITHOUT distant lymph node(s)
9 Unknown if extension or metastasis
(1) Fritz AG, Ries LAG (eds). **SEER Extent of Disease 1988: Codes and Coding Instructions (3rd Edition, 1998)**, National Cancer Institute, NIH Pub. No. 98-2313, Bethesda, MD, 1998 (2) Young JL Jr, Roffers SD, Ries LAG, Fritz AG, Hurlbut AA (eds.). **SEER Summary Staging Manual-2000: Codes and Coding Instructions**, National Cancer Institute, NIH Pub. No. 01-4969, Bethesda, MD, 2001. (3) Collaborative Stage Work Group of the American Joint Committee on Cancer. **Collaborative Stage Data Collection System User Documentation and Coding Instructions, version 02.05.** American Joint Committee on Cancer (Chicago, IL) (4) Gress, D.M., Edge, S.B., Gershenwald, J.E., et al. **Principles of Cancer Staging.** In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 3-30 (5) **Introduction to Female Reproductive Organs**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 631 (6) Erickson, B.A., Olawaiye, A.B., Mutch, D.G., et al. **Cervix Uteri**. In: Amin, M.B., Edge, S.B., Greene, F.L., et al. (Eds.) AJCC Cancer Staging Manual. 8th Ed. New York: Springer; 2017: 649-659