Histologies, Grade, Stage - AJCC 7

Notes

**Note**: The determination of AJCC stage group from T, N, and M for thyroid depends further on histologic type, grade, and age. This table shows the selection of the appropriate version of the AJCC Stage table based on histology and grade. For papillary and follicular carcinomas, a further check on age is needed to identify the correct AJCC Stage table to be used. In the table below, "Anaplastic" maps to the table AJCC-Stage: Anaplastic; "Med", to AJCC-Stage: Medullary; and "Pap/Fol", to either AJCC Stage-Thyroid: Papillary and Follicular - Age less than 45 or AJCC Stage-Thyroid: Papillary and Follicular - Age 45 and Older. If age at diagnosis is unknown, AJCC stage is derived as unknown for papillary and follicular carcinomas.
ICD-O-3 histology code Description Grade Age at Diagnosis Stage Table Stage Table 7
8020 Carcinoma, undifferentiated, NOS 1, 2, 3, 4, 9 <Any value> Anaplastic AJCC TNM7 Stage Thyroid Anaplastic
8021 Carcinoma, anaplastic, NOS 1, 2, 3, 4, 9 <Any value> Anaplastic AJCC TNM7 Stage Thyroid Anaplastic
8030 Giant cell and spindle cell carcinoma 1, 2, 3, 4, 9 <Any value> Anaplastic AJCC TNM7 Stage Thyroid Anaplastic
8031 Giant cell carcinoma 1, 2, 3, 4, 9 <Any value> Anaplastic AJCC TNM7 Stage Thyroid Anaplastic
8032 Spindle cell carcinoma 1, 2, 3, 4, 9 <Any value> Anaplastic AJCC TNM7 Stage Thyroid Anaplastic
8345 Medullary carcinoma with amyloid stroma (C73.9) 1, 2, 3, 9 <Any value> Med AJCC TNM7 Stage Thyroid Medullary
8346 Mixed medullary-follicular carcinoma (C73.9) 1, 2, 3, 9 <Any value> Med AJCC TNM7 Stage Thyroid Medullary
8347 Mixed medullary-papillary carcinoma (C73.9) 1, 2, 3, 9 <Any value> Med AJCC TNM7 Stage Thyroid Medullary
8430 Mucoepidermoid tumor [obs] 1, 2, 3, 9 <Any value> Med AJCC TNM7 Stage Thyroid Medullary
8510 Medullary carcinoma, NOS 1, 2, 3, 9 <Any value> Med AJCC TNM7 Stage Thyroid Medullary
8512 Medullary carcinoma with lymphoid stroma 1, 2, 3, 9 <Any value> Med AJCC TNM7 Stage Thyroid Medullary
8513 Atypical medullary carcinoma (C50._) 1, 2, 3, 9 <Any value> Med AJCC TNM7 Stage Thyroid Medullary
<Any value> Any histology in inclusion table 4 <Any value> Anaplastic AJCC TNM7 Stage Thyroid Anaplastic
<Any value> Any histology in inclusion table 5-8 <Any value> ERROR ERROR:
<Any value> ALL OTHER HISTOLOGIES IN INCLUSION TABLE 1, 2, 3, 9 000-044 Pap/Fol AJCC7 Stage
<Any value> ALL OTHER HISTOLOGIES IN INCLUSION TABLE 1, 2, 3, 9 045-120 Pap/Fol AJCC TNM7 Stage Thyroid Papillary and Follicular Age 45 and Older
<Any value> ALL OTHER HISTOLOGIES IN INCLUSION TABLE 1, 2, 3, 9 999 Pap/Fol Determine Validity of TNM for AJCC 7 Stage - Age at DX = 999