CS Site-Specific Factor 14

PDGFRA Gene Mutation


**Note 1**: Some gastrointestinal stromal tumors (GIST) have oncogenic mutations of the platelet-derived growth factor receptor alpha (PDGFRA)gene, located on chromosome 4q. This test is a special molecular diagnostic test performed on tumor tissue to identify PDGFRA mutations. Some GISTs that are negative for KIT mutations are positive for PDGFRA mutation. **Note 2**: Code the result of the PDGFRA gene test. Another name for PDGFRA is CD140A. **Note 3**: See CS Site-Specific Factors 12 and 13 for coding information about KIT gene expression and mutations.




NAACCR #2868
Code Description
010 PDGFRA gene test positive for mutations
020 PDGFRA gene test negative for mutations; no mutations; normal or wild-type gene
988 Not applicable: Information not collected for this case
(If this information is required by your standard setter, use of code 988 may result in an edit error.)
997 Test ordered, results not in chart; results pending
998 Test not done (test not ordered and not performed)
999 Unknown or no information
Not documented in patient record